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Nat Prod Commun ; 4(2): 271-4, 2009 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-19370937

RESUMEN

The leaf essential oils of Dendropanax capillaris, Oreopanax nubigenus and Schefflera rodrigueziana (Araliaceae) were isolated by hydrodistillation and analyzed by GC-MS. The leaf oil of Dendropanax capillaris was composed of only four compounds, beta-pinene (25.3%), 6-3-carene (44.7%), daucene (17.1%), and dauca-5,8-diene (12.9%). Oreopanax nubigenus leaf oil was dominated by the sesquiterpene hydrocarbons germacrene D (70.1%) and beta-caryophyllene (11.8%), while Schefflera rodrigueziana leaf oil was made up entirely of sesquiterpene hydrocarbons, mostly germacrene D (27.6%), beta-cubebene (27.2%), beta-caryophyllene (12.2%), beta-cubebene (11.1%), and alpha-copaene (10.8%). Both O. nubigenus and S. rodrigueziana leaf oils showed notable in-vitro cytotoxicity on MDA-MB-231 cells, which may be attributable to the relatively high concentrations of germacrene D and beta-caryophyllene in those oils.


Asunto(s)
Antineoplásicos Fitogénicos/farmacología , Araliaceae/química , Aceites Volátiles/química , Aceites de Plantas/química , Aceites de Plantas/farmacología , Antineoplásicos Fitogénicos/química , Línea Celular Tumoral , Costa Rica , Humanos , Aceites Volátiles/farmacología , Hojas de la Planta/química
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