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Métodos Terapéuticos y Terapias MTCI
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Acta Pol Pharm ; 74(2): 321-329, 2017 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29624237

RESUMEN

Capsicum annuum L. is a rich source of capsaicin, an alkaloid, which is a very pungent compound. Due to ever growing need of capsaicin, an extensive research on its efficient cultivation as well as chemical synthesis is underway. Owing to the pungent nature of capsaicin, its analogous molecules without pungent effect are being explored. The objective of this descriptive review is to comprehensively present the updates on the bioactivities of capsaicin. Additionally, the in silico target fishing approach has been used to identify the possible protein targets of capsaicin. This article will definitely provide future perspectives of research on capsaicin.


Asunto(s)
Capsaicina/uso terapéutico , Biología Computacional/métodos , Simulación por Computador , Terapia Molecular Dirigida/métodos , Transducción de Señal/efectos de los fármacos , Animales , Capsaicina/efectos adversos , Capsaicina/química , Capsaicina/farmacocinética , Humanos , Estructura Molecular , Terapia Molecular Dirigida/efectos adversos , Mapas de Interacción de Proteínas , Relación Estructura-Actividad
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