RESUMEN
BACKGROUND: Physiological lip hyperpigmentation (PLH) is a common cosmetic concern in the Middle East and Asia. It is characterized by homogeneous symmetric diffuse hyperpigmentation affecting both lips. There is no satisfactory treatment for this condition. The aim of this study is to evaluate the efficacy and safety of Q-switched (QS) 532 nm Nd:YAG laser for PLH. METHODS: A total of 30 patients with clinical diagnosis of PLH were retrospectively reviewed and included in the study. Patients underwent at least one laser treatment using QS 532 nm with a minimum follow up of six months. Laser parameters were as follows: spot size 2-3 mm, pulse duration 20 ns, fluence 2-4 J/cm2. One to three sessions were performed depending on clinical response. Two methods were used for assessment: patient satisfaction and independent physician assessment. PLH was classified as grade 1 (upper lip fully affected plus only border of lower lip), grade 2 (upper lip fully affected plus most of lower lip), and grade 3 (majority of both lips hyperpigmented). RESULTS: Excellent (>75% improvement) response was achieved in 30% of patients. Good (51-75% improvement) response was seen in 37% and 43% of patients according to patient satisfaction and independent physician assessment, respectively. Majority of patients required only one treatment session. Reactivation of herpes labialis occurred in two patients, and mottled hypopigmentation in three patients. None of the patients developed persistent hyperpigmentation or scarring. CONCLUSIONS: PLH can be effectively treated with QS 532 nm Nd:YAG laser and is well tolerated by patients.
Asunto(s)
Hiperpigmentación , Terapia por Láser , Láseres de Estado Sólido , Terapia por Luz de Baja Intensidad , Humanos , Hiperpigmentación/etiología , Hiperpigmentación/radioterapia , Terapia por Láser/efectos adversos , Terapia por Láser/métodos , Láseres de Estado Sólido/efectos adversos , Labio , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
Postburn leukoderma is challenging to treat with different surgical and nonsurgical treatments resulting in variable outcomes. We report a case of a 56-year-old female with postburn leukoderma treated successfully with topical daylight psoralen UVA therapy for 6 months. The treatment was well tolerated and showed excellent improvement. In conclusion, we report the successful use of topical daylight PUVA for postburn leukoderma with almost complete repigmentation. This is a simple, convenient, and cheap nonsurgical treatment option.
Asunto(s)
Hipopigmentación , Vitíligo , Terapia Combinada , Femenino , Ficusina , Humanos , Persona de Mediana Edad , Terapia PUVAAsunto(s)
Hiperpigmentación/prevención & control , Terapia por Luz de Baja Intensidad/efectos adversos , Papel , Protección Radiológica/métodos , Vitíligo/radioterapia , Femenino , Humanos , Hiperpigmentación/etiología , Láseres de Excímeros/uso terapéutico , Terapia por Luz de Baja Intensidad/métodos , Masculino , Vitíligo/diagnósticoRESUMEN
Polymorphous light eruption (PMLE) is the most common photodermatosis and is characterized by the development of a pruritic skin eruption within a few hours to days after sun or artificial light exposure. The eruption usually takes up to two weeks to resolve in the absence of further ultraviolet radiation. PMLE has been reported as a side effect of ultraviolet A1 (UVA1) therapy but characteristics of the eruption, especially the duration until resolution after treatment, has not been described. A 37-year-old female developed an unusually persistent PMLE that lasted for 5 weeks after completion of UVA1 phototherapy.