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1.
Int J Biol Macromol ; 251: 126418, 2023 Aug 19.
Artículo en Inglés | MEDLINE | ID: mdl-37598825

RESUMEN

This study reports the synthesis, characterization, and antibacterial activity of a novel Fe3O4 nanocomposite coated with fenugreek seed gums and silver nanoparticles (AgNPs). To enhance the antibacterial properties of AgNPs and overcome the limitations of conventional methods for the production of three-component nanocomposites, a layer of natural polymer was used. Fenugreek seed gums (FSG) were used to coat Fe3O4 NPs to prevent their decomposition and to facilitate the release of silver nanoparticles in aqueous media. The Fe3O4/FSG/Ag nanocomposites were characterized and then the antibacterial activity of the nanocomposites was evaluated against two gram-negative and two gram-positive bacteria and compared with Fe3O4, Fe3O4/FSG, FSG, and AgNO3. The results showed that the Fe3O4/FSG/Ag nanocomposites had higher antibacterial activity than the other samples and could be easily removed from treated water by a powerful magnet without causing pollution in the environment. Overall, these findings suggest that the Fe3O4/FSG/Ag nanocomposites have potential applications in water treatment for their improved antibacterial properties and ease of removal.

2.
Chem Biodivers ; 20(9): e202300811, 2023 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-37566100

RESUMEN

This study evaluated several secondary metabolites, essential oils (EOs) compositions, and antioxidant activity in four medicinal plants that originated in Isfahan rangelands. The species were Astragalus verus, Astragalus adscendens, Daphne mucronata, and Phlomis olivieri. Thirty-two genotypes of these species were evaluated for different biochemical traits. Based on the evaluation of EOs compounds, GC/MS analysis revealed the total number of identified compounds. These compounds were 25, 22, 12, and 22 for A. adscendens, A. verus, D. mucronata, and P. olivieri, respectively. The dominant compounds were phthalate (59.88 %) in A. adscendens, phytol (38.02 %) in A. verus, hexanoic acid (32.05 %) in D. mucronata and ß-cubebene (30.94 %) in P. olivieri. Phytochemical analysis showed that D. mucronata, A. adscendens, and P. olivieri had the highest total phenolics content (TPC) (18.24 mg gallic acid equivalent/g dry weight), total flavonoids content (5.57 mg QE/g DW), and total anthocyanins content (0.23 mg/g DW), respectively. The highest total chlorophyll (0.27 mg/g DW), total carotenoids (0.03 mg/g DW), and antioxidant activity (71.36 %) were observed in A. adscendens, A. adscendens and A. verus, respectively. Among all genotypes, the highest TPC (20.1 mg GAE/g DW) was observed in genotype 5 of D. mucronata. This study provided new information on the chemical compounds within the distribution range of these ecologically dominant rangeland species in Isfahan province, Iran. The data revealed that superior genotypes from these species are rich in natural antioxidants and bioactive compounds. Thus, they can be used in ethno pharmacological fields, food, and industrial applications.


Asunto(s)
Daphne , Aceites Volátiles , Phlomis , Antioxidantes/química , Aceites Volátiles/farmacología , Antocianinas , Irán , Fitoquímicos/química , Flavonoides/química , Fenoles/química , Ecosistema , Extractos Vegetales/química
3.
IET Nanobiotechnol ; 13(8): 786-799, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-31625518

RESUMEN

Along with the extensive range of exotic nanoparticle (NPs) applications, investigation of magnetic NPs (MNPs) in vitro has ushered modern antibacterial studies into an increasingly attractive research area. A great number of microorganisms exist in the size scales from nanometre to micrometre regions. The enormous potential of engineered MNPs in therapeutic procedures against various drug-resistant bacteria has declined the menace of fatal bacterial infections. Many biocompatible MNPs have been introduced that possess remarkable impacts on various bacterial strains. Conventional synthesis methods such as co-precipitation or hydrothermal techniques have been widely adopted in the production of MNPs. The MNPs for antibacterial applications are mainly required to be superparamagnetic, recyclable and biocompatible. To implement novel strategies in developing new generation antimicrobial magnetic nanomaterials, it is essential to obtain a comprehensive preview of recent achievements in synthesis, proposed antibacterial mechanisms and characterisation techniques of these nanomaterials. This review highlights notable aspects of antibacterial activity in engineered MNPs and nanocomposites including their particle properties (size, shape and saturation magnetisation), antibacterial mechanisms, synthesis methods, testing methods, surface modifications and minimum inhibitory concentrations.


Asunto(s)
Antibacterianos/uso terapéutico , Infecciones Bacterianas/tratamiento farmacológico , Nanopartículas de Magnetita/uso terapéutico , Animales , Antibacterianos/síntesis química , Antibacterianos/química , Humanos , Nanopartículas de Magnetita/química , Pruebas de Sensibilidad Microbiana , Nanocompuestos/química , Nanocompuestos/uso terapéutico
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