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Can J Diet Pract Res ; 77(2): 103-5, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26771423

RESUMEN

PURPOSE: It is commonly suggested that calcium supplementation contributes to constipation; however, little research has explored the effects of calcium supplementation on gut motility. METHODS: In an 8-week, randomized, double-blind, crossover pilot study, healthy females (n = 27, aged 43.0 ± 10.6 years) received a split dose of 500 mg/d of elemental calcium from calcium carbonate or calcium phosphate each for 2 weeks, after a 2-week baseline and separated by a 2-week washout. Participants completed daily questionnaires of stool frequency, Bristol Stool Form Scale (BSFS), and supplement intake compliance. RESULTS: There were no differences among periods. Mean ± SE stool frequency averaged 1.3 ± 0.1 stools/d in each period. Participants reported 34%, 34%, 37%, and 29% of stools were indicative of slow transit or constipation (BSFS of 1 or 2) during baseline, calcium carbonate, calcium phosphate, and washout periods, respectively. Participants also reported from 6% to 10% of stools as fast transit or diarrhea (BSFS of 6 or 7) during the periods. CONCLUSION: This study suggests that neither calcium carbonate nor calcium phosphate, providing 500 mg/d of calcium, affects stool frequency or form. Although stool frequency was normal, the healthy females participating in the study experienced stools indicating slow (constipation) and fast (diarrhea) transit.


Asunto(s)
Calcio de la Dieta/administración & dosificación , Calcio de la Dieta/efectos adversos , Estreñimiento/diagnóstico , Suplementos Dietéticos , Adulto , Índice de Masa Corporal , Carbonato de Calcio/administración & dosificación , Carbonato de Calcio/efectos adversos , Fosfatos de Calcio/administración & dosificación , Fosfatos de Calcio/efectos adversos , Estreñimiento/etiología , Estudios Cruzados , Relación Dosis-Respuesta a Droga , Método Doble Ciego , Heces/química , Femenino , Voluntarios Sanos , Humanos , Persona de Mediana Edad , Proyectos Piloto , Encuestas y Cuestionarios
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