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J Biomed Biotechnol ; 2009: 394592, 2009.
Artículo en Inglés | MEDLINE | ID: mdl-19756159

RESUMEN

The effect of Hibiscus sabdariffa L. (Hs) calyx extract on fat absorption-excretion and body weight in rats, was investigated. Rats were fed with either a basal diet (SDC = Control diet) or the same diet supplemented with Hs extracts at 5%, 10% and 15% (SD(5), SD(10) and SD(15)). Only SD(5) did not show significant increases in weight, food consumption and efficiency compared to SD(C). The opposite occurred in SD(15) group which showed a significant decrease for these three parameters. The SD(10) responses were similar to SD(15), with the exception of food consumption. In both SD(C) and SD(5) groups, no body weight loss was observed; however, only in the latter group was there a significantly greater amount of fatty acids found in feces. A collateral effect emerging from the study is that components of Hs extract at the intermediate and greater concentrations used in this experiment could be considered possible antiobesity agents.


Asunto(s)
Ácidos Grasos/metabolismo , Flores/química , Hibiscus/química , Metabolismo de los Lípidos/efectos de los fármacos , Extractos Vegetales/farmacología , Aumento de Peso/efectos de los fármacos , Absorción , Análisis de Varianza , Animales , Etanol/química , Ácidos Grasos/orina , Heces/química , Masculino , Extractos Vegetales/química , Ratas , Ratas Sprague-Dawley
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