RESUMEN
A new naphthalene derivative, named eucleanal (1), was isolated from Euclea divinorum Hiern., and its structure elucidated by detailed spectroscopic (1H, 13C NMR, COSY, HMQC, HMBC) and HREIMS analysis.
Asunto(s)
Ebenaceae/química , Naftalenos/química , Estructura MolecularRESUMEN
A new flavone dimer, drypetdimer A (1), was isolated from Drypetes gerrardii J.Hutch The structure of the new compound was elucidated by detailed spectroscopic analysis such as 1H, 13C NMR, COSY, HMQC, HMBC and HREIMS.
Asunto(s)
Euphorbiaceae/química , Flavonas/química , Estructura MolecularRESUMEN
The methanolic extract of the fresh root bark and berries of Solanum aculeastrum showed significant activity against host snails of schistosomiasis. The berries extract was more potent with 100% snail kill at 50 ppm. Fractionation increased activity with 100% mortality at 20 ppm. The aqueous and methanolic extracts of the berries showed moderate antimicrobial activity, increasing by fractionation.
Asunto(s)
Antibacterianos/farmacología , Biomphalaria/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Moluscocidas/farmacología , Fitoterapia , Extractos Vegetales/farmacología , Solanum , Animales , Antibacterianos/administración & dosificación , Antibacterianos/uso terapéutico , Frutas , Humanos , Moluscocidas/administración & dosificación , Moluscocidas/uso terapéutico , Extractos Vegetales/administración & dosificación , Extractos Vegetales/uso terapéutico , Raíces de Plantas , Esquistosomiasis/tratamiento farmacológicoRESUMEN
From the roots of the plant Tephrosia aequilata Baker, five flavonoids were isolated of which, 3,4:8,9-dimethylenedioxypterocarpan is reported for the first time. Its structure and those of the already known flavonoids were established by physical and spectroscopic analysis. Application of 2D NMR techniques was useful for complete characterization of the new pterocarpan as well as the other known flavonoids.