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1.
Nutrients ; 14(20)2022 Oct 16.
Artículo en Inglés | MEDLINE | ID: mdl-36297014

RESUMEN

BCAAs supplementation has been widely used for post-exercise recovery. However, no evidence is currently available to answer the question of whether BCAAs supplementation can attenuate muscle damage and ameliorate recovery after a bout of change of direction (COD) sprinting, which is an exercise motion frequently used during team sport actions. This study aimed to assess the effect of BCAAs supplementation on muscle damage markers, subjective muscle soreness, neuromuscular performance, and the vascular health of collegiate basketball players during a 72 h recovery period after a standardized COD protocol. Participants orally received either BCAAs (0.17 g/kg BCAAs + 0.17 g/kg glucose) or placebo (0.34 g/kg glucose) supplementation before and immediately after a COD exercise protocol in a randomized, crossover, double-blind, and placebo-controlled manner. Creatine kinase increased immediately after exercise and peaked at 24 h, muscle soreness remained elevated until 72 h, whilst arterial stiffness decreased after exercise for both supplemented conditions. A negligibly lower level of interleukin-6 was found in the BCAAs supplemented condition. In conclusion, the results of this study do not support the benefits of BCAAs supplementation on mitigating muscle damage and soreness, neuromuscular performance, and arterial stiffness after COD for basketball players.


Asunto(s)
Aminoácidos de Cadena Ramificada , Mialgia , Humanos , Creatina Quinasa/metabolismo , Suplementos Dietéticos , Método Doble Ciego , Glucosa/metabolismo , Interleucina-6/metabolismo , Músculo Esquelético/metabolismo , Mialgia/prevención & control , Mialgia/tratamiento farmacológico , Estudios Cruzados
2.
Nutrients ; 13(8)2021 Aug 17.
Artículo en Inglés | MEDLINE | ID: mdl-34444975

RESUMEN

This review evaluated the effects of milk-based protein supplementation on resistance training (RT)-induced gains in lean body mass or fat free mass (LBM/FFM) and muscle strength for older adults. A systematic search of PubMed, Scopus and EBSCOhost/SPORTDiscus was conducted. Eligibility criteria: Randomized controlled trials comparing all types of milk-based protein supplements with control supplements for the training older adults at mean age ≥ 60 y. Twenty studies were included in the qualitative synthesis, whilst seventeen studies were included in the quantitative synthesis. A dose of 10-15 g of milk protein supplementation was sufficient to augment RT-induced LBM/FFM. Intriguingly, four out of five studies show negative effect of whey protein supplementation at the same dose range (or even higher) compared with control supplementation (-0.49 kg, 95% CI: -0.69, -0.29, I2 = 14%, Z = 4.82, p < 0.001). For milk-based protein supplementation, RT-induced improvements in muscle strength were observed only when the protein doses ≥22 g (+0.66 kg, 95% CI: 0.07, 1.25, I2 = 0%, Z = 2.18, p = 0.03). Conclusion: Milk protein is superior to whey protein in enhancing RT-induced LBM/FFM gains for older adults. Optimal daily protein intake can dilute the protein supplementation effect.


Asunto(s)
Composición Corporal/efectos de los fármacos , Suplementos Dietéticos , Proteínas de la Leche/farmacología , Fuerza Muscular/efectos de los fármacos , Músculo Esquelético/efectos de los fármacos , Entrenamiento de Fuerza , Anciano , Anciano de 80 o más Años , Compartimentos de Líquidos Corporales/efectos de los fármacos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Proteína de Suero de Leche/farmacología
3.
Nutrients ; 13(6)2021 May 31.
Artículo en Inglés | MEDLINE | ID: mdl-34072718

RESUMEN

Previous studies have reported the positive effects of branched-chain amino acids (BCAAs) supplementation on lowering plasma markers of muscle damage and subjective soreness after resistance exercise. However, a variety of factors can potentially moderate its efficacy. This meta-analysis aimed to summarize the evidence regarding the effect of BCAAs supplementation on plasma muscle damage markers and soreness after resistance exercise in only trained males, by considering the plasma lactate dehydrogenase (LDH) and creatine kinase (CK). Randomized controlled trials were identified through a computerized literature search for the period 2010-2020. The pooled data were analyzed with the random-effects model and heterogeneity using I2. Cochrane Collaboration tools was used for the assessment of risk of bias. Nine studies met the inclusion criteria. A positive effect was found for CK at <24, 24, and 48 h after exercise and for muscle soreness at <24 h only. However, the positive effect was not evident for plasma LDH at any follow-up time. Different outcomes for post-exercise responses may suggest that BCAAs supplementation can attenuate muscle damage and ameliorate muscle soreness after resistance exercise in trained males.


Asunto(s)
Aminoácidos de Cadena Ramificada , Suplementos Dietéticos , Músculo Esquelético/efectos de los fármacos , Mialgia/tratamiento farmacológico , Adulto , Aminoácidos de Cadena Ramificada/administración & dosificación , Aminoácidos de Cadena Ramificada/farmacología , Aminoácidos de Cadena Ramificada/uso terapéutico , Atletas , Humanos , Masculino , Ensayos Clínicos Controlados Aleatorios como Asunto , Adulto Joven
4.
J Sports Med Phys Fitness ; 60(5): 685-692, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-32438784

RESUMEN

BACKGROUND: Falls prevention is a critical goal of training program for older individuals. This study explored the effects of a judo program on gait performance in older adults. METHODS: Pre- and post-intervention (15 weeks, 1-hr session, twice a week) step length (cm), gait cycle time (s), speed (m·s-1) and cadence (step·min-1) mean values (AVG) and coefficients of variation (CV) were assessed in a judo (JG: N.=16 novice judoka; age=69.3±3.9 years) and a control (CG: N.=14 healthy older adults; age=70.1±4.5 years) group. Two 3 (motor complexity: flat, corridor, hurdling) ×2 (group: JG, CG) ×2 (time: pre, post) MANOVAs with repeated measures were applied to ascertain differences in gait parameters. RESULTS: A significant Time×Motor Complexity×Group interaction was found for AVG and CV. For AVG, JG showed improvements for flat and hurdling conditions in step length (flat: ∆=+2.6%, d=0.4; hurdling: ∆=+3.2%, d=0.4), gait cycle (flat: ∆=-4.3%, d=0.4; hurdling: ∆=-4.0%, d=0.5), speed (flat: ∆=+6.6%, d=0.7; hurdling: ∆=+6.7%, d=0.6) and cadence (flat: ∆=4.3%, d=0.4; hurdling: ∆=3.9%, d=0.5). For CV, JG improved step length for flat (∆=-20.9%, d=0.6) and hurdling (∆=-16.3%, d=0.8) conditions, whereas CG showed a deterioration in the step length for the corridor condition (∆=+22.3%, d=0.7). CONCLUSIONS: The findings demonstrated the effectiveness of an adapted judo program for improving gait performance in older individuals, suggesting a potential protective effect for fall risk.


Asunto(s)
Accidentes por Caídas/prevención & control , Análisis de la Marcha/métodos , Artes Marciales/fisiología , Anciano , Estudios de Casos y Controles , Ejercicio Físico/fisiología , Femenino , Humanos , Masculino , Equilibrio Postural/fisiología
6.
J Strength Cond Res ; 33(10): 2882-2896, 2019 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-29239994

RESUMEN

Ciaccioni, S, Condello, G, Guidotti, F, and Capranica, L. Effects of judo training on bones: a systematic literature review. J Strength Cond Res 33(10): 2882-2896, 2019-The aim of this study was to provide a systematic literature review on the osteogenic effects of judo (PROSPERO: CRD42016041803). The online search was conducted according to the inclusion criteria: observational studies and clinical/interventional trials in English from inception to June 2016; bone health, bone mineral density (BMD), diameters, impact force, and bone turnover marker (BTM) outcomes. Thirty-four studies were included and graded for their methodological quality ("fair" quality: 79.4%). The most used assessment method (44.1%) was X-ray absorptiometry. A positive association between judo and bone health/status emerged. Findings support site-specific BMD accrual in children, adolescents, adult athletes, and in premenopausal and postmenopausal female practitioners. Bone turnover markers revealed a hypermetabolic status in high-level judo athletes. The osteogenic stimuli of judo seem to protect athletes from alterations in bone metabolic balance due to weight loss cycling. Sexual dimorphism was found between judoka in bone diameters and mass, and significant differences in bone breadths emerged between elite and nonelite judokas. The fall techniques reduced bone impact force and velocity with respect to "natural" fall. Further longitudinal, cross-sectional, and interventional researches are required. This article provides useful information on bone for health sport scientists, coaches, and practitioners, stimulating future research lines on judo. In particular, coaches and physical trainers should consider introducing judo fall techniques in their training plans to prevent fall-related injuries, especially relevant in the older population. Conversely, coaches are urged to carefully control weight cycling dietary habits of their athletes, which can produce serious metabolic responses on bones.


Asunto(s)
Densidad Ósea , Huesos/fisiología , Artes Marciales/fisiología , Absorciometría de Fotón , Biomarcadores/sangre , Peso Corporal , Humanos
7.
Molecules ; 22(9)2017 Sep 20.
Artículo en Inglés | MEDLINE | ID: mdl-28930188

RESUMEN

The aim of this work was to demonstrate that a natural compound, not-toxic to normal cells, has cytotoxic and sensitizing effects on carcinoma cells, with the final goal of combining it with chemotherapeutic drugs to reduce the overall dose. Prunus spinosa Trigno ecotype (PsT) drupe extract with a nutraceutical activator complex (NAC) made of amino acids, vitamins and mineral salt blends, has shown in vitro anticancer activity. The cytotoxic effect of (PsT + NAC)® has been evaluated on human cancer cells, with an initial screening with colorectal, uterine cervical, and bronchoalveolar cells, and a subsequent focus on colon carcinoma cells HCT116 and SW480. The viability reduction of HCT116 and SW480 after treatment with (PsT 10 mg/mL + NAC)® was about 40% (p < 0.05), compared to control cells. The cell's survival reduction was ineffective when the drug vehicle (NAC) was replaced with a phosphate buffer saline (PBS) or physiological solution (PS). The flow cytometry evaluation of cancer cells' mitochondrial membrane potential showed an increase of 20% depolarized mitochondria. Cell cycle analysis showed a sub G1 (Gap 1 phase) peak appearance (HCT116: 35.1%; SW480: 11.6%), indicating apoptotic cell death induction that was confirmed by Annexin V assay (HCT116: 86%; SW480: 96%). Normal cells were not altered by (PsT + NAC)® treatments.


Asunto(s)
Antineoplásicos/farmacología , Apoptosis/efectos de los fármacos , Extractos Vegetales/farmacología , Prunus/química , Antineoplásicos/química , Línea Celular Tumoral , Supervivencia Celular/efectos de los fármacos , Fase G1/efectos de los fármacos , Humanos , Potencial de la Membrana Mitocondrial/efectos de los fármacos , Extractos Vegetales/química
8.
Medicine (Baltimore) ; 96(28): e7272, 2017 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-28700470

RESUMEN

The aim of this study was to assess the stress-related responses and the coach's capability to match perceived efforts of youth athletes during a taekwondo championship.Using a cross-sectional study design, salivary cortisol (sC) and alpha-amylase (sAA) were measured in 6 males and 3 females young (11.0 ±â€Š0.9 years) athletes at awakening, 5 minutes before, and 1 minute and 30 minutes after official combats. State anxiety was recorded 60 minutes before the first competition, whereas coach's and athletes' ratings of perceived exertion (RPE) were obtained at the end of the combats. Time-matched (awakening and pre-competition) salivary samples and trait anxiety were collected 7-day postcompetition during a resting day.No effect for match outcome emerged. No difference emerged between athletes and coach RPEs. Higher (P = .03) state anxiety (41.6 ±â€Š10.9 points) was shown than trait anxiety (34.8 ±â€Š7.1 points). Time-matched sAA were similar. Peak sAA observed at the end of the combat (114.2 ±â€Š108.1 U/mL) was higher (P < .01) than the other samples (range: 20.6-48.1 U/mL), whereas sC increased (P < .05) from awakening (8.0 ±â€Š1.5 nmol/L), with peak levels observed at 30 minutes into the recovery phase (19.3 ±â€Š4.3 nmol/L). Furthermore, pre-competition sC (16.5 ±â€Š4.5 nmol/L) values were higher (P < .01) with respect to time-matched samples during the resting day (4.6 ±â€Š1.0 nmol/L). The 3 athletes engaged in consecutive matches showed a tendency toward increasing sAA and sC.Taekwondo combats pose a high stress on young athletes, eliciting a fast reactivity of the sympathetic-adreno-medullary system relative to the hypothalamic-pituitary-adrenocortical system. Understanding the athlete's efforts during combats, coaches are recommended to apply effective recovery strategies between matches.


Asunto(s)
Ansiedad/metabolismo , Atletas/psicología , Hidrocortisona/metabolismo , Artes Marciales/fisiología , Artes Marciales/psicología , alfa-Amilasas Salivales/metabolismo , Ansiedad/etiología , Niño , Conducta Competitiva/fisiología , Femenino , Humanos , Masculino , Actividad Motora/fisiología , Percepción , Pruebas Psicológicas , Saliva/metabolismo , Factores de Tiempo
9.
J Strength Cond Res ; 28(4): 1151-7, 2014 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-24077373

RESUMEN

The purpose of this study was to define the technical and tactical profiles of official youth taekwondo competitions played under the most recent rules of the International Taekwondo Federation. Tactical actions (i.e., attack, defense, and block), technical executions (from 1- to 4-point scores), kicking legs (i.e., front/rear and right/left), and overall technical effectiveness were investigated in relation to match outcome of semifinal and final competitions (n = 50) of youth (aged 13-14 years) black belt athletes during the Italian Taekwondo Cadet Championship. Differences (p < 0.001) were found among all action typologies (Attack: 50.9 ± 2.2%; Defense: 27.7 ± 1.5%; Block: 21.3 ± 1.6%), with winners showing fewer (p = 0.005) offensive actions and more (p = 0.001) defensive actions with respect to non-winners. Independently from match outcome, technical exchanges showed differences (p < 0.001) for technical executions. Winners resulted more efficient (p < 0.001) for both technical and tactical variables. In general, these findings showed that Cadets tend to adopt an offensive strategy. In considering that the adoption of the new electronic system requires athletes to execute correct technical actions to have a score assigned, coaches should emphasize the effectiveness of scoring techniques and help athletes to effectively improve their defense and counterattack capabilities.


Asunto(s)
Rendimiento Atlético/fisiología , Artes Marciales/fisiología , Educación y Entrenamiento Físico/métodos , Adolescente , Conducta Competitiva/fisiología , Femenino , Humanos , Italia , Masculino , Artes Marciales/psicología , Tiempo de Reacción , Estudios de Tiempo y Movimiento
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