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1.
Zhongguo Zhong Yao Za Zhi ; 43(6): 1254-1260, 2018 Mar.
Artículo en Chino | MEDLINE | ID: mdl-29676137

RESUMEN

To evaluate the report quality of intervention-related systematic reviews or Meta-analysis published in China Journal of Chinese Materia Medica, we searched CNKI and China Journal of Chinese Materia Medica webpages to collect intervention-related systematic reviews or Meta-analysis since the first issue of the magazine. A total of 40 systematic reviews or Meta-analysis reports were included, including one network Meta-analysis. According to the PRISMA statement published in 2009, the report quality of the systematic reviews or Meta-analysis was evaluated. According to the results, 3 had the low quality, 30 had the medium quality, and 7 had the high quality. The average score for all of items was 30 points (21-30.5 points for the medium quality). The 17 high-quality (31-40 points) report items were title, rationale, objectives, information sources, study selection, data collection process, data items, risk of bias in individual studies, summary measures, risk of bias across studies, study selection, study characteristics, risk of bias within studies, results of individual studies, synthesis of results, risk of bias across studies and funding; the 4 medium-quality (21-30.5 points) reporting items were eligibility criteria, search, limitations and conclusions; and the 6 low-quality (<=20.5 points) reporting items were structured summary, protocol and registration, synthesis of results, additional analysis (No.16), additional analysis (No.23) and summary of evidence. Through the analysis, it is found that the report quality of intervention-related systematic reviews or Meta-analysis published in China Journal of Chinese Materia Medica is medium, and it is necessary to improve the quality standard of the report.


Asunto(s)
Metaanálisis como Asunto , Revisiones Sistemáticas como Asunto , Bibliometría , China
2.
Pharmacol Ther ; 117(2): 280-95, 2008 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-18048101

RESUMEN

Ischemia and reperfusion (I/R) exerts multiple insults in microcirculation, frequently accompanied by endothelial cell injury, enhanced adhesion of leukocytes, macromolecular efflux, production of oxygen free radicals, and mast cell degranulation. Since the microcirculatory disturbance results in injury of organ involved, protection of organ after I/R is of great importance in clinic. Salvia miltiorrhiza root has long been used in Asian countries for clinical treatment of various microcirculatory disturbance-related diseases. This herbal drug contains many active water-soluble compounds, including protocatechuic aldehyde (PAl), 3,4-dihydroxyphenyl lactic acid (DLA) and salvianolic acid B (SalB). These compounds, as well as water-soluble fraction of S. miltiorrhiza root extract (SMRE), have an ability to scavenge peroxides and are able to inhibit the expression of adhesion molecules in vascular endothelium and leukocytes. Moreover, lipophilic compounds of SMRE also prevent the development of vascular damage; NADPH oxidase and platelet aggregation are inhibited by tanshinone IIA and tanshinone IIB, respectively, and the mast cell degranulation is blunted by cryptotanshinone and 15,16-dihydrotanshinone I. Thus, the water-soluble and lipophilic compounds of SMRE appear to improve the I/R-induced vascular damage multifactorially and synergically. This review will summarize the ameliorating effect of compounds derived from SMRE on microcirculatory disturbance and target organ injury after I/R and will provide a new perspective on remedy with multiple drugs.


Asunto(s)
Encéfalo/irrigación sanguínea , Fármacos Cardiovasculares/farmacología , Medicamentos Herbarios Chinos/farmacología , Riñón/irrigación sanguínea , Hígado/irrigación sanguínea , Pulmón/irrigación sanguínea , Extractos Vegetales/farmacología , Daño por Reperfusión/tratamiento farmacológico , Salvia miltiorrhiza , Animales , Plaquetas/efectos de los fármacos , Fármacos Cardiovasculares/química , Fármacos Cardiovasculares/aislamiento & purificación , Fármacos Cardiovasculares/uso terapéutico , Degranulación de la Célula/efectos de los fármacos , Circulación Cerebrovascular/efectos de los fármacos , Circulación Coronaria/efectos de los fármacos , Citocinas/metabolismo , Medicamentos Herbarios Chinos/uso terapéutico , Células Endoteliales/efectos de los fármacos , Humanos , Leucocitos/efectos de los fármacos , Circulación Hepática/efectos de los fármacos , Mastocitos/efectos de los fármacos , Microcirculación/efectos de los fármacos , Estructura Molecular , Daño por Reperfusión Miocárdica/tratamiento farmacológico , Daño por Reperfusión Miocárdica/fisiopatología , Extractos Vegetales/uso terapéutico , Raíces de Plantas , Circulación Renal/efectos de los fármacos , Daño por Reperfusión/metabolismo , Daño por Reperfusión/fisiopatología , Salvia miltiorrhiza/química
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