RESUMEN
The fruits of Piper tuberculatum yielded pellitorine, N-isobutyl-2E,4E-decadienamide (1), and piperidide-2E,4E-decadienamide (2). Their complete NMR analysis, based on one- and two-dimensional experiments, is reported.
Asunto(s)
Ácidos Grasos Insaturados/química , Plantas Medicinales/química , Frutas , Humanos , Espectroscopía de Resonancia Magnética , Extractos Vegetales/química , Alcamidas PoliinsaturadasRESUMEN
From the stem bark of Bowdichia virgilioides, lupeol, lupeol acetate, sitosterol, stigmasterol and methyl-3-[2-(1-hydroxymethylvinyl)-2,3-dihydrobenzo[b]furan-5-yl]-(E)-2-propenoate have been isolated. The latter is a new compound and it has been named as bowdenol. Their structures were elucidated with the aid of spectroscopic techniques, mostly 1 and 2D NMR. The biogenetic pathway for bowdenol has been suggested.
Asunto(s)
Benzofuranos/aislamiento & purificación , Fabaceae/química , Plantas Medicinales/química , Acrilatos/química , Acrilatos/metabolismo , Benzofuranos/química , Brasil , Catálisis , Cromatografía en Capa Delgada , Ácidos Cumáricos/química , Ácidos Cumáricos/metabolismo , Estructura Molecular , Resonancia Magnética Nuclear Biomolecular , Corteza de la Planta/química , Tallos de la Planta/química , Ácido Shikímico/química , Ácido Shikímico/metabolismo , Espectrofotometría Infrarroja , Espectrofotometría Ultravioleta , Fosfatos de Azúcar/química , Fosfatos de Azúcar/metabolismo , Tirosina/química , Tirosina/metabolismoRESUMEN
A new phenylcoumarone type trinorlignan, krametosan (1), along with the known norlignans, ratanhiaphenol I (2) and 2-(2'-hydroxy-4',6'-dimethoxyphenyl)-5-(E)-propenylbenzofuran (3), the lignan conocarpan (4) and dinorlignan decurrenal (5), were isolated from the CHCl3 extract of the roots of Krameria tomentosa. The structure of these compounds were elucidated by the spectroscopic methods.
Asunto(s)
Benzofuranos/aislamiento & purificación , Furanos , Lignanos/aislamiento & purificación , Magnoliopsida/química , Plantas Medicinales/química , Benzofuranos/química , Brasil , Cromatografía en Capa Delgada , Lignanos/química , Estructura Molecular , Resonancia Magnética Nuclear Biomolecular , Raíces de Plantas/químicaRESUMEN
A systematic search for solasodine, an important starting material for the partial synthesis of steroidal hormones as well as other potentially bioactive constituents of various Solanum species of Brazil has been undertaken. Thus, the fruits of S. paludosum, S. asperum, S. sessiliflorum and Solanum sp. were found to contain significant amounts of solasodine. The root bark of S. paludosum which showed curare like activity yielded tomatidenol and another yet unidentified alkaloid responsible for the biological activity. The fruits of S. asperum yielded a new spirosolane alkaloid, solaparnaine. The stem bark of S. pseudo-quina showed convulsive and excitatory activity from which (25S)-isosolafloridine was identified as the active principle. In addition, the latter alkaloid was also found to show antimicrobial activity.
Asunto(s)
Plantas Medicinales/química , Alcaloides Solanáceos/aislamiento & purificación , Antiinfecciosos/aislamiento & purificación , Brasil , Alcaloides Solanáceos/farmacología , Esteroides/aislamiento & purificación , Esteroides/farmacologíaRESUMEN
A systematic search for solasodine, an important staring material for the partial synthesis of steroidal hormones as well as other potentially bioactive constituents of various Solanum species of Brazil has been undertaken. Thus, the fruits of S. paludosum, S. asperum, S. sessiliforum and Solanum sp. were found to contain significant amounts of solasodine. The root bark of S. paludosum which showe durare like activity yelded tomatidenol and another yet unidentified alkaloid responsible for the biological activity. The fruits of S. asperum yelded a new spirosolane alkaloid, solaparnaine. The stem bark of S. pseudo-quina showed convulsive and exitatory activity from which (25S)-isosolafloridine was identified as the active principle. In addition, the latter alkaloid was also found to show antimicrobial activity.