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1.
Int J Vitam Nutr Res ; 91(1-2): 77-86, 2021 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31726948

RESUMEN

Vitamins and carotenoids are organic compounds that are important for vital functions of the human organism. Since the human body is not able to synthesize most of these micronutrients, they need to be supplied by the intake of food or supplements. The aim of this study was to analyze whether a whole food based, encapsulated fruit, berry, and vegetable juice powder concentrate provides bioavailable carotenoids and vitamins A (all-trans retinol), E and C. Eighteen healthy subjects received 6 capsules a day for 8 weeks, which provided 2.91 mg ß-carotene, 490 µg vitamin A, 18.7 mg vitamin E, 159 mg vitamin C, 6.1 mg lutein and 1 mg lycopene. Plasma concentrations of several carotenoids and vitamins before and after supplementation were measured. After 8 weeks of supplementation, the plasma concentration of the following carotenoids increased significantly: α-carotene increased from 59.6 ± 22.4 nmol/L to 85.7 ± 24.2 nmol/L (p = 0.002), ß-cryptoxanthin from 106.7 ± 39.8 nmol/L to 151.9 ± 57.9 nmol/L (p = 0.017), and lycopene from 1.2 ± 0.5 µmol/L to 1.7 ± 0.5 µmol/L (p = 0.005). Significant increases were also observed for plasma concentrations of vitamin C from 70 ± 20 µmol/L to 90 ± 10 µmol/L (p < 0.001), all-trans retinol from 1.99 ± 0.24 µmol/L to 2.30 ± 0.66 µmol/L (p = 0.015), and α-tocopherol from 27 ± 6 µmol/L to 32 ± 6 µmol/L (p = 0.008). For those micronutrients with accepted plasma reference ranges, all observed increases levelled off around the upper limit of the individual reference range. The data demonstrate that the investigated supplement is able to increase plasma concentrations of certain carotenoids and vitamins of healthy subjects within 8 weeks.


Asunto(s)
Verduras , Vitamina A , Carotenoides , Frutas , Humanos , Plasma , Polvos , Vitaminas
2.
Int J Food Sci Nutr ; 71(6): 769-780, 2020 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-32064970

RESUMEN

The major aim of this controlled, randomised, open-labelled, parallel-grouped, clinical trial was to investigate whether supplementation with different dosages of omega-3 fatty acids (0.5 g/d and 1 g/d) from a plant-based fatty acid supplement affected omega-3-indices (O3I) in well-nourished, healthy people. In addition, the combined ingestion of the plant-based fatty acid supplement, together with an encapsulated fruit, vegetable and berry (FVB) juice powder concentrate, was applied in order to observe the absorption of certain micronutrients and to examine some aspects related to the safe consumption of the products. The data demonstrate that the intake of only 0.5 g/day of omega-3 fatty acids from of a vegan supplement was able to increase the O3I significantly after 8 and 16 weeks. The combined ingestion with the FVB supplement concurrently increased serum concentrations of specific vitamins and carotenoids without effects on hepatic, kidney and thyroid function or changes in blood lipids.


Asunto(s)
Suplementos Dietéticos , Ácido Eicosapentaenoico/sangre , Ácidos Grasos Omega-3/administración & dosificación , Ácidos Grasos Insaturados/sangre , Micronutrientes/sangre , Fenómenos Fisiológicos de la Nutrición , Extractos Vegetales/administración & dosificación , Adulto , Austria , Disponibilidad Biológica , Cápsulas , Relación Dosis-Respuesta a Droga , Ácidos Grasos Omega-3/farmacocinética , Femenino , Jugos de Frutas y Vegetales , Voluntarios Sanos , Humanos , Masculino , Persona de Mediana Edad , Extractos Vegetales/farmacocinética , Polvos
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