RESUMEN
The present study examined the effect of several extracts of Visnea mocanera L. on the bleeding time and gastrointestinal transit in mice using the Duke test and charcoal meal method, respectively; they were also investigated in order to examine their renal effects. Results showed that V. mocanera extracts significantly inhibited both the bleeding time and gastrointestinal transit in mice. No diuretic activity of these extracts were detected. In contrast, they significantly reduced the urine volume. The study provides experimental support to the therapeutic advocation of V. mocanera in ethnomedicine for the treatment of diarrhoea and the healing of wounds.
Asunto(s)
Diuresis/efectos de los fármacos , Tránsito Gastrointestinal/efectos de los fármacos , Extractos Vegetales/farmacología , Animales , Tiempo de Sangría , Carbón Orgánico/administración & dosificación , Electrólitos/orina , Masculino , Ratones , Ratas , Ratas Wistar , EspañaRESUMEN
A chemical study of Visnea mocanera leaves was carried out giving lupeol and beta-sitosterol fatty esters, as well as beta-sitosterol and the triterpenic betulinic, ursolic, platanic and 2 alpha,3 beta-dihydroxy-ursan-12-en-28-oic and 2 alpha,3 beta-dihydroxy-olean-12-en-28-oic acids. Studies of the antimicrobial activity of acetone and methanol extracts as well as an aqueous infusion were also performed and the good experimental results obtained justify the folk use of this species as a cicatrizant and vulnerary agent.
Asunto(s)
Antiinfecciosos/aislamiento & purificación , Extractos Vegetales/aislamiento & purificación , Antiinfecciosos/análisis , Antiinfecciosos/farmacología , Antifúngicos/aislamiento & purificación , Antifúngicos/farmacología , Humanos , Medicina Tradicional , Pruebas de Sensibilidad Microbiana , Extractos Vegetales/análisis , Extractos Vegetales/farmacologíaRESUMEN
The qualitative and quantitative determination of the essential oils of the aerial part of two varieties of Cedronella canariensis (L.) W. et B., namely, C. canariensis var. canariensis and C. canariensis var. anisata have been performed, together with the study of the antimicrobial activity of both oils. The noteworthy inhibition exhibited against Bordetella bronchiseptica and Cryptococcus albidus may justify the popular use of the these plants in the treatment of certain diseases of the respiratory tract.
Asunto(s)
Bacterias/efectos de los fármacos , Hongos/efectos de los fármacos , Aceites Volátiles/farmacología , Aceites de Plantas/farmacología , Plantas Medicinales/química , Cromatografía de Gases , Cromatografía de Gases y Espectrometría de Masas , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Pruebas de Sensibilidad Microbiana , Aceites Volátiles/química , Aceites de Plantas/químicaRESUMEN
A chemotherapeutic study has been carried out on thirteen products Eeleven diterpenes, one lignan, (+)-sesamin, and a coumarin, siderin] isolated from SALVIA and SIDERITIS species considered endemic to the Canarian flora. The data obtained suggest that some diterpenoid compounds show an interesting cytostatic activity, specially galdosol ( 6) with an ID (50) value of 0.5 microg/ml. These compounds also evidence a moderate antibacterial activity against Gram positive bacteria.
RESUMEN
We present in this paper a report of 155 species used for medicinal purpose in the Canary Islands. These species have been compiled in 13 tables in accordance with their main medicinal use, indicating also other possible popular uses. We have made a short inventory of the rates of the most important medicinal applications. This new compilation shows once more the traditional use of the phytotherapeutic resources by the Canary population and also the wide possibilities of the phytochemical and pharmacological investigations of the Canary Islands Flora.
Asunto(s)
Plantas Medicinales , Islas del Atlántico , Etnología , FarmacologíaRESUMEN
A large amount of ethnobotanical data of almost 200 botanical species used for medicinal purposes in the Canary Islands is presented. We are endeavouring to avoid the definitive loss of the islands' phytotherapeutic heritage, in view of the rapid social changes taking place over the last few years and hope that this work may serve to promote further pharmacological research that may confirm, scientifically and experimentally, the information presented here. A brief description of the geographical, botanical and historical circumstances is included. The species listed have been classified according to a basically therapeutical criterion.
Asunto(s)
Medicina Tradicional , Plantas Medicinales/análisis , Analgésicos , Antiinflamatorios , Antitusígenos , Islas del Atlántico , Catárticos , Clima , Diuréticos , Expectorantes , Fármacos Gastrointestinales , Historia del Siglo XVIII , Historia del Siglo XIX , Historia del Siglo XX , Historia Antigua , Historia Medieval , Humanos , Hipoglucemiantes , Medicina Tradicional/historia , Parasimpatolíticos , Tranquilizantes/farmacologíaRESUMEN
The chemotherapeutic study of a limited series of steroidal sapogenins from several endemic species of the flora of the Canary Islands is presented here. On the whole, they possess a very weak antibacterial activity, a slight antifungal effect and one of them, vespertilin, displays interesting cytostatic activity (ID50 = 5 micrograms/ml). A pharmacodynamic screening carried out on this product mainly revealed very slight toxicity, antihistaminic activity and a light tranquilizing effect. The data obtained justify further research.