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Métodos Terapéuticos y Terapias MTCI
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Indian J Med Sci ; 65(3): 92-9, 2011 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-23250289

RESUMEN

OBJECTIVE: The plant Argemone mexicana is traditionally used as diuretic, anti-inflammatory, antibacterial, antifungal agent, and has wound-healing property. This study was carried out to evaluate the effect of A. mexicana aerial part of the plant (methanolic and aqueous extract p.o.) on duodenal ulceration. MATERIALS AND METHODS: The study was carried out on the duodenal ulceration model by using cysteamine hydrochloride. Ranitidine (20 mg/kg) was used as standard drug. RESULTS: Both the extracts of the plant A. mexicana produced a significant activity in cysteamine-induced duodenal ulceration. The aqueous extract at the dose-dependent manner showed the potent activity than methanolic extract. CONCLUSION: The plant A. mexicana Linn. Increased healing of gastric ulceration and prevented the development of experimentally induced duodenal ulceration in rats.


Asunto(s)
Argemone , Úlcera Duodenal/tratamiento farmacológico , Fitoterapia/métodos , Extractos Vegetales/uso terapéutico , Animales , Cisteamina/toxicidad , Modelos Animales de Enfermedad , Úlcera Duodenal/inducido químicamente , Masculino , Ratas , Ratas Wistar , Resultado del Tratamiento
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