Status and correlates of micronutrient deficiencies in slum and non-slum areas of India's four metropolitan cities: Investigation from CNNS.

Micronutrient malnutrition is an emerging public health concern globally. It affects people of all ages and socioeconomic groups; however, the most marginalized are the worst affected. Using data from the Comprehensive National Nutrition Survey 2016-18, we determined the magnitude of deficiencies (of iron, zinc, vitamin A, folate, vitamins B12 and D) among children and adolescents (1-19 years of age) living in four metropolitan cities of India. Separate estimates by residence in slum and non-slum areas were derived for pre-school and school-aged children and adolescents. The association between each micronutrient deficiency (MND) and place of residence, exposure to progarmmes, socioeconomic, and demographic variables was assessed using Poisson regression. Of all children in the sample, at least seven out of 10 children suffered from some kind of MND. Anaemia was prevalent among all children but at different levels among various age-groups. Folate deficiency was highly prevalent among children in slums whereas deficiencies of vitamin D and zinc were more prevalent among non-slum children. Dietary diversity reduced the risk of deficiencies- Vitamin A in children 1-9, anaemea in 1-4 age, folate in children 5-19. Exposure to government-sponsored nutrition programmes such as mid-day meal, and IFA did not show any significant effect on reducing deficiencies. However, adolescents exposed to IFA supplementation programmes were less likely to be folate deficient. Overall, government schemes that have been running for decades, and intensified lately, are yet to show noticeable positive effect on micronutrient status of children. Nevertheless, differential estimates by slum/non-slum residence and by age-groups calls for devising different strategies for different sub-groups to address the issue of MNDs among children and adolescents. Nutrition education not only for slum residents but also for those from non-slum areas is an urgent need to check the spread of MNDs.

Co-existence of diabetes and TB among adults in India: a study based on National Family Health Survey data.

Multiple studies suggest that diabetes mellitus (DM) is a potential risk factor for tuberculosis (TB) development and treatment, especially in low- and middle-income countries. The study aimed to test concomitancy between DM and TB among adults in India. Data were from the 2015-16 National Family Health Survey (NFHS-4). The study sample comprised 107,575 men aged 15-54 and 677,292 women aged 15-49 for which data on DM status were available in the survey. The association between state-level prevalence of TB and DM was examined and robust Poisson regression analysis applied to examine the effect of DM on TB. A high prevalence of TB was observed among individuals with diabetes in India in 2015-16. A total of 866 per 100,000 men and 405 per 100,000 women who self-reported having diabetes also had TB; among those who self-reported not having diabetes the ratios were 407 per 100,000 men and 241 per 100,000 women. The risk of having TB among those who self-reported having DM was higher for both men (2.03, 95% CI: 1.26, 3.28) and women (1.79, 95% CI: 1.48, 2.49) than for those who did not self-report having DM. Adults who were diagnosed with diabetes (including pre-diabetes) also had a higher rate of TB (477 per 100,000 men and 331 per 100,000 women) than those who were not diagnosed (410 per 100,000 men and 239 per 100,000 women). Adults from poor families, with lower BMIs, lower levels of literacy and who were not working had a higher risk of TB-DM co-morbidity. The state-level pattern of co-morbidity, the under-reporting of DM (undiagnosed) and TB stigmatization are discussed. The study confirms that diabetes is an important co-morbid feature with TB in India, and reinforces the need to raise awareness on screening for the co-existence of DM and TB with integrated health programmes for the two conditions.

Integrating HIV Pre-Exposure Prophylaxis into Family Planning Care: A RE-AIM Framework Evaluation.

We aimed to systematically evaluate the feasibility of integrating HIV prevention services, including pre-exposure prophylaxis (PrEP), into a family planning setting in a high-prevalence community. We used the RE-AIM Framework (Reach, Efficacy, Adoption, Implementation, Maintenance) to evaluate the integration of HIV prevention services into a family planning clinic over 6 months. Before the integration, PrEP was not offered. We implemented a staff training program on HIV PrEP. We determined the proportion of women presenting to the clinic who were screened, eligible for, and initiated PrEP through chart review. We assessed staff comfort with PrEP pre- and post-integration. We compared planned and actual implementation, interviewed staff to determine barriers and facilitators, and tracked systems adaptations. We assessed maintenance of PrEP after the study concluded. There were 640 clinical encounters for 515 patients; the rate of HIV counseling and PrEP screening was 50%. The rate was 10% in month 1 and peaked to 65% in month 3. Nearly all screened patients were eligible for PrEP (98.4%) and 15 patients (6%) initiated PrEP. Staff knowledge and comfort discussing PrEP improved after education. Facilitators included partnering with local experts, continuing education, clinical tools for providers, and patient education materials. Barriers included competing priorities during clinical encounters, limited woman-centered patient education materials, and insurance-related barriers. Embedding HIV prevention services in the family planning setting was feasible in this pilot. The proportion of women screened for PrEP rapidly increased. In this high HIV prevalence community, nearly all screened women were eligible and 6% initiated PrEP.