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J Am Acad Dermatol ; 83(1): 123-130, 2020 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-32165196

RESUMEN

BACKGROUND: A systematic review failed to identify any systemic therapy used in alopecia areata (AA) where use is supported by robust evidence from high-quality randomized controlled trials. OBJECTIVE: To produce an international consensus statement on the use and utility of various treatments for AA. METHODS: Fifty hair experts from 5 continents were invited to participate in a 3-round Delphi process. Agreement of 66% or greater was considered consensus. RESULTS: In the first round, consensus was achieved in 22 of 423 (5%) questions. After a face-to-face meeting in round 3, overall, consensus was achieved for only 130 (33%) treatment-specific questions. There was greater consensus for intralesional treatment of AA (19 [68%]) followed by topical treatment (25 [43%]). Consensus was achieved in 45 (36%) questions pertaining to systemic therapies in AA. The categories with the least consensus were phototherapy and nonprescription therapies. LIMITATIONS: The study included a comprehensive list of systemic treatments for AA but not all treatments used. CONCLUSION: Despite divergent opinions among experts, consensus was achieved on a number of pertinent questions. The concluding statement also highlights areas where expert consensus is lacking and where an international patient registry could enable further research.


Asunto(s)
Alopecia Areata/terapia , Administración Oral , Administración Tópica , Corticoesteroides/uso terapéutico , Factores de Edad , Alopecia Areata/tratamiento farmacológico , Terapia Combinada , Terapias Complementarias , Técnica Delphi , Fármacos Dermatológicos/uso terapéutico , Testimonio de Experto , Humanos , Inyecciones Intralesiones , Fototerapia , Índice de Severidad de la Enfermedad , Resultado del Tratamiento
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