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To analyze the study advance of Cichorium intybus, a kind of medicinal food, this study systematically retrieved Chinese and English literatures of C.intybus-related studies based on CNKI and the Web of Science database platforms by literature metrological research method and CiteSpace 5.5.R2 software, and visualized the literatures. A total of 1 247 Chinese literatures and 1 488 English literatures were included. Author analysis showed that HAN Yongfen in Guizhou Grass Industry Research Institute and W VAN DEN ENDE in Belgium Catholic University of Leuven had the most publications in Chinese and English C.intybus literatures respectively. ZHANG Bing's team was the core study team of C. intybus in China. Beijing University of Chinese Medicine and Belgium Catholic University of Leuven had the largest number of Chinese and English Cichorium literatures. There was a few cooperation between Chinese study institutions and close cooperation between foreign research institutions. Keywords analysis showed that C.intybus studies mainly focused on breeding and growth performance, composition analysis and content determination, nutritional value and medicinal value, in which C.intybus composition and its role in reducing uric acid were the hotspots of current studies. This study found that C.intybus has a high economic value and medicinal value, and its food nutrition and medicinal activity will be the main directions of future studies.
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Cichorium intybus , Beijing , China , Bases de Datos Factuales , Programas InformáticosRESUMEN
Objective:To analyze the research status of gouty arthritis at home and abroad in the past 15 years，and to provide reference for for further in-depth research in this field. Method:With “Gouty arthritis” as the research topic, the related papers during 2004—2019 were searched in Web of science core collection database and CNKI databases respectively. The results were statistically sorted out according to publication year，author，institution，literature source and key words，etc，and were visualized by CiteSpace software. Result:A total of 5 071 Chinese papers and 1 136 English papers were included. The amount of domestic and foreign publications continued to rise，forming a core team represented by LI Zhao-fu，XIONG Hui，SCHLESINGER NAOMI and other authors. The research hotpots focused on the pathogenesis，diagnosis methods， Chinese and Western medicine treatment，clinical observation，risk assessment and other aspects of gouty arthritis. Both of them had their own emphases. Domestic researches tended to focus on the treatment of gouty arthritis with traditional Chinese medicine，while foreign ones focused on the pathological research and clinical investigation of gouty arthritis. Conclusion:The number of researches in the field of gouty arthritis is on the rise as a whole，and there are both consistency and differences in the research content and hot topics between domestic and foreign literature. Therefore， we should strengthen cooperation and exchange between different teams and countries，so as to promote the overall development of this field.
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Based on the pharmacovigilance thoughts of Chinese medicine of cognition, application, prevention and rescue of drug toxicity, to sort out the pharmacovigilance information in representative herbal works of the Ming dynasty, and to analyze the characteristics of the pharmacovigilance thoughts of the Ming dynasty, so as to provide reference for rational drug use in modern clinical practice. Taking Bencao Pinhui Jingyao, Bencao Gangmu, Paozhi Dafa, Bencao Shengya Banjie, Bencao Mengquan as the blueprints, and taking the traditional Chinese medicines in these books as the research objects, the text information was extracted from the four aspects of drug identification, drug use, drug prevention and detoxification, and the idea of pharmacovigilance was summarized. In Ming dynasty, pharmacovigilance had a systematic understanding, and cognition of drug toxicity was clear in identifying poison and correcting the mistakes of predecessors, in the aspects of using and preventing poisons, the use of poisons was prominent, the compatibility and process of poisons were emphasized, and the methods and mechanism of poison relief were clear in detoxification. Ming dynasty has initially formed the whole pharmacovigilance theoretical frame of cognition, application, prevention and rescue of drug toxicity, which has certain guiding and reference significance for modern clinical rational drug use.