RESUMEN
Licania tomentosa is a Brazilian plant species that produces edible fruits, yet there is little information available concerning their nutritional and/or bioactive composition. This study aimed to evaluate the nutritional and polyphenol composition of L. tomentosa fruits (pulp and seeds) and measure antioxidant activity in ethanolic extracts.The pulp and seeds were excellent sources of fiber (25.62%-41.70%) as well as minerals and vitamins. L. tomentosa contained no lectins or protease inhibitors (chymotrysin and trypsin) and 12 polyphenol compounds were identified in the seed extracts with a predominance of flavonoids. The seeds also presented antioxidant activities using the DPPH (SC5010.30-15.87 µg/mL), TBARS (IC50 18.46-20.84 µg/mL), and FRAP (RC50 0.203-0.309 µg/mL) assays. Due to its nutrient and antioxidant content, L. tomentosa may be used for food applications.
Asunto(s)
Antioxidantes/química , Chrysobalanaceae/química , Valor Nutritivo , Extractos Vegetales/química , Brasil , Cromatografía Líquida de Alta Presión , Chrysobalanaceae/metabolismo , Flavonoides/química , Harina/análisis , Frutas/química , Frutas/metabolismo , Polifenoles/análisis , Polifenoles/química , Inhibidores de Proteasas/análisis , Inhibidores de Proteasas/química , Semillas/química , Semillas/metabolismo , Espectrometría de Masa por Ionización de ElectrosprayRESUMEN
Studies have shown the benefit of antioxidants in the prevention or treatment of human diseases and promoted a growing interest in new sources of plant antioxidants for pharmacological use. This study aimed to add value to two underexploited wild plant species (Licania rigida) and L. tomentosa) from Brazilian flora. Thus, the phenolic compounds profile of their seed ethanol extract and derived fractions were elucidated by HPLC, the antioxidant capacity was assessed by in vitro chemical tests and the cytotoxicity determined using the human carcinoma cell lines MCF-7 and Caco-2. Eleven phenolic compounds were identified in the extracts of each species. The extracts and fractions showed excellent antioxidant activity in the DPPH assay (SC50, ranging from 9.15 to 248.8 µg/mL). The aqueous fraction of L. rigida seeds was most effective in preventing lipid peroxidation under basal conditions (IC50 60.80 µg/mL) whereas, in the presence of stress inducer, the methanolic fraction of L. tomentosa performed best (IC50 8.55 µg/mL). None of the samples showed iron chelating capacity. Ethanolic seed extracts of both species did not reveal any cytotoxicity against MCF-7 and Caco-2 cells. Both plant species showed a promising phenolic profile with potent antioxidant capacity and deserve attention to be sustainably explored.