1.
Cancer Chemother Pharmacol
; 1(4): 255-7, 1978.
Artículo
en Inglés
| MEDLINE
| ID: mdl-373922
RESUMEN
Nineteen patients with non-small-cell carcinoma of the lung were treated with high-dose methotrexate and leucovorin rescue. Two partial responses (10.5%) were observed, lasting 13 and 17 weeks. Toxicity was acceptable. It is concluded that the occasional benefit of high-dose methotrexate with leucovorin rescue at this dose and according to the schedule described for these patients does not warrant further study.