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Métodos Terapéuticos y Terapias MTCI
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1.
Blut ; 36(4): 239-45, 1978 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-274161

RESUMEN

When ficoll purified peripheral blood lymphocytes were treated with fluorescein conjugated lectins from lentils (LCH), castor beans (RCA) and phaseolus coccineus beans (L-and E-PHA) for 15 min and the percentages of the cap forming cells were examined, the values of leukemic lymphocytes were reduced compared to the values obtained with normal lymphocytes. The reduction was more than half in patients with acute and chronic myelogenous leukemia and immunoblastoma, it was only one quarter in patients with chronic lymphocytic leukemia, Hodgkin's disease and lymphosarcoma. The lowest number of cap forming cells was found in lymphoblasts of established lymphoblastoid cell lines. The four different lectins showed nearly the same capacity in the induction of caps. After successive binding, the different lectins showed cocapping on the lymphocyte surface.


Asunto(s)
Lectinas/farmacología , Leucemia/sangre , Linfocitos/efectos de los fármacos , Linfoma/sangre , Adolescente , Adulto , Anciano , Ricinus communis , Fabaceae , Enfermedad de Hodgkin/sangre , Humanos , Leucemia Linfoide/sangre , Leucemia Mieloide/sangre , Leucemia Mieloide Aguda/sangre , Linfoma no Hodgkin/sangre , Persona de Mediana Edad , Lectinas de Plantas , Plantas Medicinales , Plantas Tóxicas
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