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Sci Rep ; 11(1): 17985, 2021 09 09.
Artículo en Inglés | MEDLINE | ID: mdl-34504229

RESUMEN

This study clarifies the role of refugia and landscape permeability in the formation of the current genetic structure of peoples of the Caucasus. We report novel genome-wide data for modern individuals from the Caucasus, and analyze them together with available Paleolithic and Mesolithic individuals from Eurasia and Africa in order (1) to link the current and ancient genetic structures via landscape permeability, and (2) thus to identify movement paths between the ancient refugial populations and the Caucasus. The ancient genetic ancestry is best explained by landscape permeability implying that human movement is impeded by terrain ruggedness, swamps, glaciers and desert. Major refugial source populations for the modern Caucasus are those of the Caucasus, Anatolia, the Balkans and Siberia. In Rugged areas new genetic signatures take a long time to form, but once they do so, they remain for a long time. These areas act as time capsules harboring genetic signatures of ancient source populations and making it possible to help reconstruct human history based on patterns of variation today.


Asunto(s)
Genoma Humano , Genómica/métodos , Genotipo , Migración Humana/historia , Población Blanca/genética , Cromosomas Humanos Y/genética , ADN/genética , ADN/aislamiento & purificación , Bases de Datos Genéticas , Flujo Genético , Variación Genética , Georgia (República) , Historia del Siglo XXI , Historia Antigua , Humanos , Masculino , Linaje , Refugiados/historia , Federación de Rusia , Turquía
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