Effect of PTSD treatment on cardiovascular reactivity during trauma memory recall and correspondence with symptom improvement.

ABSTRACTBackground: Prior research has shown PTSD treatment leads to reductions in cardiovascular reactivity during trauma recall, but the extent to which such reductions are associated with changes in PTSD symptoms is less clear. Moreover, such relationships have not been investigated in a cognitively focused PTSD treatment.Objective: To examine changes in cardiovascular reactivity to the trauma memory in patients receiving cognitive processing therapy (CPT), CPT with a written trauma account, and a written account only condition. We also examined the association of such changes with symptom improvement.Method: 118 women with PTSD secondary to interpersonal violence completed pre- and post-treatment assessments of PTSD symptoms and cardiovascular reactivity during a script-driven imagery task.Results: Results indicated a significant but modest reduction in cardiovascular reactivity in CPT conditions. Changes in cardiovascular reactivity and reexperiencing symptoms were significantly associated among the whole sample. Among individuals with the greatest reactivity to the trauma memory at pretreatment, associations were also seen with changes in total PTSD, numbing, and trauma-related guilt.Conclusions: Results indicate that previous findings on the effect of PTSD treatment on cardiovascular reactivity during trauma recall extend to cognitively oriented treatment. Baseline cardiovascular reactivity may influence the extent to which reductions in PTSD symptoms and reactivity during trauma recall are related.

Cognitive Processing Therapy leads to reduced heart rate reactivity when recalling a trauma memory.Decreases in heart rate reactivity are associated with reduced reexperiencing symptoms.Changes in heart rate reactivity and PTSD symptoms are more closely related among patients with greater pretreatment reactivity.

The effects of cognitive processing therapy + hypnosis on objective sleep quality in women with posttraumatic stress disorder.

Objective: Insomnia, characterized by difficulty falling and staying asleep, is a common and debilitating symptom of posttraumatic stress disorder (PTSD) that is resistant to first-line, trauma-focused therapies. Previous research has found that sleep-directed hypnosis improves subjective sleep quality, particularly sleep onset latency, in women with PTSD. However, it cannot be assumed that improvements in subjective sleep reports correspond with objectively measured sleep improvements, because research has indicated a lack of agreement across these measures. The current study examined the effects of sleep-directed hypnosis plus cognitive processing therapy (hypCPT) on objective indices of sleep quality measured with actigraphy. Method: Forty-five women with PTSD were randomized to receive sleep-directed hypCPT or sleep and psychiatric symptom monitoring plus CPT (ssmCPT). Pre- and posttreatment, participants completed 1 week of daily actigraphy assessments of nocturnal sleep onset latency, waking after sleep onset, and total sleep time. Results: Overall improvement in objective sleep indices was not observed. Despite this, at posttreatment, treatment completers receiving hypCPT took significantly less time to fall asleep than did women receiving ssmCPT. Conclusions: More research is needed to understand and reduce the discrepancy between subjectively and objectively assessed sleep impairments in PTSD. Nevertheless, results indicate that adding sleep-directed hypnosis to trauma-focused therapy may be of some use for individuals with PTSD-related insomnia. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

Prospectively predicting PTSD status with heart rate reactivity and recovery in interpersonal violence survivors.

The current study used heart rate (HR) reactivity to personalized trauma cues and HR recovery to predict later Posttraumatic Stress Disorder (PTSD) status in female interpersonal violence survivors. A scripted imagery paradigm was used to assess initial (M = 1 month posttrauma) HR reactivity during exposure to and recovery following idiographic trauma cues. In addition, follow-up PTSD status (M = 8 months posttrauma) was assessed with the Clinician Administered PTSD scale (CAPS). A logistic regression was used to predict PTSD status at the follow-up assessment with HR reactivity during exposure to a personalized trauma audio script and recovery periods at initial assessment entered hierarchically. Script HR reactivity alone did not significantly predict PTSD status. However, after adding HR recovery, the model was significant. Higher HR during recovery was significantly positively associated with PTSD-positive status while script HR reactivity remained a non-significant predictor. The model correctly classified 70% of cases with PTSD. A second logistic regression with initial CAPS severity as a covariate showed that HR recovery added predictive value beyond acute PTSD symptoms. These results suggest that HR recovery following trauma cue exposure is an important predictor of PTSD development.