[Use of transcranial electroanalgesia for treating spondylogenic pain syndromes]. / Primenenie transkranial'noi élektroanal'gezii dlia lecheniia spondilogennykh bolevykh sindromov.

The analgesic effect of the net transcutaneous application to the brain of constant and impulse currents (the frequency of rectangular impulses was 77 Hz, the duration of an impulse, 3.5 ms) in a 2-5:1 ratio was investigated. An analgesic effect was observed in both healthy subjects and in patients with spondylogenic pain. The duration of analgesic effect following a 30-minute therapeutic session was 6-10 hours. A 5-7 session course was associated with a gradual increase and stabilization of the analgesic effect. The procedure was attended by no complications.

[Neurochemical aspects of therapeutic electric stimulation]. / Neirokhimicheskie aspekty lechebnoi élektricheskoi stimuliatsii.

Comparative analysis of the CSF and blood protein-peptide composition in Parkinsonian patients performed with the aid of indwelled electrodes prior to and after therapeutic electrical stimulation (TES) of the brain subcortical structures, revealed a therapeutic effect in the form of reduced muscular rigidity and a mental activation with a positive emotional response. After the TES the protein content in the biological fluids tended to become normalized and the the range of low-molecular protein-peptide fractions changed. A high-performance liquid chromatography, bidimensional electrophoresis and thin-layer chromatography revealed about 5-6 factors of peptide nature with the molecular mass less than 5000 daltons in the CSF and blood after the TES. These factors were shown to exert a biological effect upon muscle preparation of the leech.