RESUMEN
We report a case of severe liver injury occurring on two occasions in a patient ingesting large doses of nicotinic acid. The liver architecture was markedly distorted, with both massive and submassive lobular collapse and marked cholestasis. Complete resolution of biochemical and histologic abnormalities occurred after withdrawal of these drugs.
Asunto(s)
Enfermedad Hepática Inducida por Sustancias y Drogas/etiología , Niacina/efectos adversos , Adulto , Colestasis/inducido químicamente , Humanos , Hígado/patología , Pruebas de Función Hepática , MasculinoRESUMEN
Red cell aplasia and an enlarging anterior mediastinal mass developed in a patient being followed for thyroid carcinoma. Differential diagnosis included thymoma and metastatic thyroid carcinoma. Preoperative scanning demonstrated significant uptake of 75Se-selenomethionine whereas 67Ga-galiium citrate failed to visualize the mass. Subsequent thoracotomy revealed a lymphocytic thymoma which was resected, resulting in reversal of the red cell aplasia. The use of 75Se-selenomethionine scanning maybe a useful adjunct in the preoperative evaluation of suspected thymomas.