RESUMEN
Twelve patients with known or suspected pituitary lesions underwent MR imaging with gadodiamide injection at a dose of 0.1 (n = 5) or 0.3 (n = 7) mM/kg. Six of the patients were also studied with 0.1 mM/kg gadopentetate dimeglumine. Consistent with previous reports gadodiamide injection was found to be a safe and effective contrast medium for MR imaging of the pituitary region. No additional diagnostic information was obtained using 0.3 mM/kg gadodiamide injection compared to 0.1 mM/kg gadopentate dimeglumine in the same patients. The high dose (0.3 mM/kg) gadodiamide injection in 7 patients did not shorten the T2 value sufficiently to overwhelm the T1 shortening and leave pathologic lesions hypointense compared to precontrast studies. With the comparable relaxivities of gadodiamide injection and gadopentetate dimeglumine, similarities in results have to be expected when using these media for MR image enhancement.
Asunto(s)
Medios de Contraste , Gadolinio , Imagen por Resonancia Magnética , Compuestos Organometálicos , Ácido Pentético/análogos & derivados , Enfermedades de la Hipófisis/diagnóstico , Adenoma/diagnóstico , Adulto , Anciano , Medios de Contraste/administración & dosificación , Craneofaringioma/diagnóstico , Combinación de Medicamentos , Femenino , Gadolinio/administración & dosificación , Gadolinio DTPA , Humanos , Aumento de la Imagen , Inyecciones Intravenosas , Imagen por Resonancia Magnética/métodos , Masculino , Meglumina , Persona de Mediana Edad , Compuestos Organometálicos/administración & dosificación , Ácido Pentético/administración & dosificación , Neoplasias Hipofisarias/diagnóstico , Prolactinoma/diagnóstico , Estudios RetrospectivosRESUMEN
Barium peritonitis secondary to perforation of the gut is an infrequent complication of radiological G-I tract examinations. It is thought to imply a high mortality rate. However, this conception seems to be based on data obtained during the early 1950's. More recent case reports and small series indicate a more favourable prognosis depending on effective antibiotics and successful maintenance of severely ill patients. The scant information concerning the fate of pediatric cases warranted presentation of the experience of 5 patients, who all survived. Our approach to treatment and the suggested use of barium studies, in particular barium enema, in obscure abdominal emergency cases are offered.