RESUMEN
The effects of water to solids ratio (WSR, 10-30 mL/g), power (180-540 W), and irradiation time (IT, 5-15 min) in microwave-assisted extraction (MAE) were optimized to extract polysaccharides from melon peels (PMP). The maximum extraction yield (32.81 %) was obtained under 20.94 mL/g WSR, 414.4 W power, and 12.75 min IT. The main monosaccharide composition of purified PMP with an average molecular weight of 5.71 × 104 kDa were d-galacturonic acid, arabinose, glucose, and galactose. An ascending dose-dependent antiradical and antioxidant behavior for PMP (0-5.0 mg/mL) was found. The initial foaming capacity (38.6-110.3 %) and foaming stability (5.2-65.2 %) were significantly increased as a function of PMP concentration (1.0-5.0 %), while they reduced by increasing the mixing time (p < 0.05). The highest emulsifying activity index (44.1 m2/g) and emulsifying stability (69.3 %) at 5.0 % PMPs were determined. PMP gels with FTIR-identified functional groups can be formulated in new gluten-free functional products.
Asunto(s)
Antioxidantes/química , Cucumis melo/química , Extracción Líquido-Líquido/métodos , Pectinas/química , Polisacáridos/química , Antioxidantes/aislamiento & purificación , Arabinosa/química , Arabinosa/aislamiento & purificación , Compuestos de Bifenilo/antagonistas & inhibidores , Compuestos de Bifenilo/química , Emulsiones , Análisis Factorial , Frutas/química , Galactosa/química , Galactosa/aislamiento & purificación , Geles , Glucosa/química , Glucosa/aislamiento & purificación , Ácidos Hexurónicos/química , Ácidos Hexurónicos/aislamiento & purificación , Humanos , Microondas , Peso Molecular , Picratos/antagonistas & inhibidores , Picratos/química , Extractos Vegetales/química , Polisacáridos/aislamiento & purificación , ResiduosRESUMEN
Coronavirus disease 2019 (COVID-19) is the current major health crisis in the world. A successful strategy to combat the COVID-19 pandemic is the improvement of nutritional pattern. Garlic is one of the most efficient natural antibiotics against the wide spectrum of viruses and bacteria. Organosulfur (e.g., allicin and alliin) and flavonoid (e.g., quercetin) compounds are responsible for immunomodulatory effects of this healthy spice. The viral replication process is accelerated with the main structural protease of SARS-CoV-2. The formation of hydrogen bonds between this serine-type protease and garlic bioactives in the active site regions inhibits the COVID-19 outbreak. The daily dietary intake of garlic and its derived-products as an adjuvant therapy may improve side effects and toxicity of the main therapeutic drugs with reducing the used dose.