RESUMEN
Eight megastigmane glycosides were isolated from the leaves of Myrsine seguinii collected in Okinawa. Three of them were found to be known compounds, i.e., ampelopsisionoside, alangionoside J, and linarionoside A. The structures of the new megastigmane glycosides were elucidated from the spectroscopic data and their absolute stereochemistries were determined in detail using a modified Mosher's method.
Asunto(s)
Glicósidos/química , Hojas de la Planta/química , Plantas Medicinales/química , Acetilación , Glicósidos/aislamiento & purificación , Hidrólisis , Espectroscopía de Resonancia Magnética , Extractos Vegetales , Solventes , Espectrometría de Masa Bombardeada por Átomos Veloces , Espectrofotometría InfrarrojaRESUMEN
New megastigmane (1) and tetraketide (2) were isolated from the leaves of Euscaphis japonica and the structures were elucidated by means of spectroscopic and chemical evidence.
Asunto(s)
Ciclohexanonas/química , Disacáridos/química , Glucósidos/química , Norisoprenoides , Plantas Medicinales/química , Ciclohexanonas/aislamiento & purificación , Disacáridos/aislamiento & purificación , Glucósidos/aislamiento & purificación , Espectroscopía de Resonancia Magnética , Hojas de la Planta/química , Espectrometría de Masa Bombardeada por Átomos VelocesRESUMEN
Extensive isolation work on the n-BuOH-soluble fraction obtained from the leaves of Premna subscandens, collected on Ishigaki island, Okinawa, afforded six compounds. Two were identified as megastigmane glucosides, 7-(3,5-dihydroxy-1,1,5-trimethylcyclohexylidene)-9-methylprop++ +-8-enyl 9-O-beta-D-glucopyranoside and 3-hydroxy-5,6-epoxy-beta-ionol 9-O-beta-D-glucopyranoside. The structures of the remaining four new compounds were elucidated to be a 2'-O-beta-D-apiofuranosyl derivative of 3-hydroxy-5,6-epoxy-beta-ionol 9-O-beta-D-glucopyranoside, named premnaionoside, benzyl alcohol beta-D-(2'-O-beta-D-xylopyranosyl)glucopyranoside, phenethyl alcohol beta-D-(2'-O-beta-D-glucopyranosyl)glucopyranoside, and 4,4'-dimethoxy-beta-truxinic acid catalpol diester by spectroscopic analyses.
Asunto(s)
Ciclobutanos/aislamiento & purificación , Glucósidos/aislamiento & purificación , Extractos Vegetales/química , Hojas de la Planta/química , Acetilación , Ciclobutanos/química , Ciclohexanoles/química , Ciclohexanoles/aislamiento & purificación , Furanos/química , Furanos/aislamiento & purificación , Glucósidos/química , Espectroscopía de Resonancia Magnética , Modelos Químicos , Espectrometría de Masa Bombardeada por Átomos VelocesRESUMEN
As a part of the search for biologically active plant products, M cells, which form a collagen fiber network in vitro after a prolonged culture period, were used. The n-BuOH-soluble fraction of a methanol extract of leaves of Premna subscandens exhibited promotion of collagen network formation by M cells. Extensive isolation work guided by a bioassay afforded a phenylethanoid, acteoside, as an active compound.
Asunto(s)
Colágeno/metabolismo , Plantas Medicinales/química , Línea Celular , Colorantes , Humanos , Espectroscopía de Resonancia Magnética , Filipinas , Extractos Vegetales/farmacología , Hojas de la Planta/química , Estimulación QuímicaRESUMEN
From the water-soluble fraction of a methanol extract of leaves of Alangium premnifolium, two new megastigmane glycosides, alangionosides N and O, along with three known megastigmane glycosides, dendranthemoside A and alangionosides A and B, were isolated. Shimaurinosides A and B, xylopyranosyl(1-->6)glucopyranosides of simple alcohols were also found to be constituents of the water-soluble fraction. Structures were determined by spectroscopic analyses.
Asunto(s)
Alcoholes/química , Glicósidos/química , Extractos Vegetales , Alcoholes/aislamiento & purificación , Secuencia de Carbohidratos , Glicósidos/aislamiento & purificación , Espectroscopía de Resonancia Magnética , Datos de Secuencia Molecular , Rotación Óptica , Hojas de la Planta , Relación Estructura-ActividadRESUMEN
From the leaves of Duranta erecta, four new iridoid glucosides, duranterectosides A, B, C and D, were isolated along with durantosides I and II, lamiide, lamiidoside and verbascoside. Duranterectoside A was also isolated from the stems together with durantosides I, II and III, and lamiidoside. The structures of the new compounds were elucidated based on the spectroscopic evidence.