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1.
BMC Health Serv Res ; 23(1): 683, 2023 Jun 22.
Artículo en Inglés | MEDLINE | ID: mdl-37349759

RESUMEN

BACKGROUND: The main causes of morbidity and mortality for adolescents and young adults are preventable and stem from psychosocial and behavioural concerns. Psychosocial assessments can help clinicians to identify and respond holistically to risks and strengths that may impact upon a young person's physical and mental health. Despite broad support at a policy level, the implementation of routine psychosocial screening for young people remains varied in Australian health settings. The current study focused on the pilot implementation of a digital patient-completed psychosocial assessment (the e-HEEADSSS) at the Sydney Children's Hospital Network. The aim of this research was to evaluate patient and staff barriers and facilitators to local implementation. METHODS: The research used a qualitative descriptive research design. Semi-structured interviews were conducted online with 8 young patients and 8 staff members who had completed or actioned an e-HEEADSSS assessment within the prior 5 weeks. Qualitative coding of interview transcripts was carried out in NVivo 12. The Consolidated Framework for Implementation Research guided the interview framework and qualitative analyses. RESULTS: Results demonstrated strong support for the e-HEEADSSS from patients and staff. Key reported facilitators included strong design and functionality, reduced time requirements, greater convenience, improved disclosure, adaptability across settings, greater perceived privacy, improved fidelity, and reduced stigma for young people. The key barriers were related to concerns over available resources, the sustainability and continuity of staff training, perceived availability of clinical pathways for follow-up and referrals, and risks related to off-site completions. Clinicians need to adequately explain the e-HEEADSSS assessment to patients, educate them about it, and make sure that they receive timely feedback on the results. Greater reassurance and education regarding the rigour of confidentiality and data handling procedures is required for patients and staff. CONCLUSIONS: Our findings indicate that continued work is required to support the integration and sustainability of digital psychosocial assessments for young people at the Sydney Children's Hospital Network. The e-HEEADSSS shows promise as an implementable intervention to achieve this goal. Further research is required to determine the scalability of this intervention across the broader health system.


Asunto(s)
Hospitales Pediátricos , Salud Mental , Niño , Humanos , Adolescente , Adulto Joven , Australia , Motivación
2.
J Pediatr Nurs ; 30(5): e11-4, 2015.
Artículo en Inglés | MEDLINE | ID: mdl-26044910

RESUMEN

This paper discusses the importance of holistic person-centered care coordination services for young people with type 1 diabetes as they transition to adult health services. In response to the growing need for comprehensive, flexible, person-centered care for young people with chronic conditions, the new service Trapeze: a supported leap into adult health was established. Based in Sydney, Australia, Trapeze is a specialist adolescent chronic care service offering comprehensive care coordination services to young people with chronic conditions aged 14-25 years. Trapeze aims to support young people with type 1 diabetes by focusing on the individual needs of the young person and developing a mutually recognized relationship based on trust and respect, in order to facilitate a process whereby a young person feels safe enough to discuss some of the challenges they face in self-management, keeping their whole of life issues central to this process. The importance of holistic person-centered work is best exemplified through the stories of the young people enrolled in Trapeze. It is hoped that through the 'eyes' of the young people and by sharing their stories the approach to self-management and care coordination can be better understood.


Asunto(s)
Diabetes Mellitus Tipo 1/psicología , Diabetes Mellitus Tipo 1/terapia , Atención Dirigida al Paciente/organización & administración , Calidad de Vida , Transición a la Atención de Adultos/organización & administración , Adaptación Psicológica , Adolescente , Australia , Diabetes Mellitus Tipo 1/diagnóstico , Humanos , Cuidados a Largo Plazo , Relaciones Enfermero-Paciente , Grupo de Atención al Paciente/organización & administración , Muestreo , Perfil de Impacto de Enfermedad , Adulto Joven
3.
Bioorg Med Chem Lett ; 16(4): 1065-9, 2006 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-16290143

RESUMEN

A series of novel five-membered urea derivatives as potent NK1 receptor antagonists is described. The effects of substitution of a 4-fluoro group at the phenyl ring and the introduction of an alpha-methyl group at the benzylic position to improve potency and duration of in vivo activity are discussed. Several compounds with high affinity and sustained in vivo activity were identified.


Asunto(s)
Ansiolíticos/química , Ansiolíticos/farmacología , Antagonistas del Receptor de Neuroquinina-1 , Urea/análogos & derivados , Urea/farmacología , Animales , Ansiolíticos/síntesis química , Alcoholes Bencílicos/química , Cristalografía por Rayos X , Evaluación Preclínica de Medicamentos , Flúor/química , Gerbillinae , Modelos Moleculares , Estructura Molecular , Actividad Motora/efectos de los fármacos , Relación Estructura-Actividad , Urea/síntesis química
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