1.
Zhong Yao Cai
; 36(4): 645-9, 2013 Apr.
Artículo
en Chino
| MEDLINE
| ID: mdl-24134014
RESUMEN
OBJECTIVE: To optimize the formulation of Eisemia foetida protein (EFP) burn spray. METHODS: A five-factor, three-level response surface method was employed; The response variable was the proliferation effect of EFP on NIH3T3 cells. RESULTS: The optimization formulation was as follows: the proportion of EFP, glycerol and mannitol was 0.91%, 1.42% and 5%, respectively; 0.02 mol/L Na2 HPO4 and 0.01 mol/L citric acid buffer system corresponding pH value was 7.0. CONCLUSION: The response surface method is reliable, efficient and suitable for optimizing the formulation of EFP burn spray.