Asunto(s)
Síndrome de Inmunodeficiencia Adquirida/complicaciones , Ciprofloxacina/uso terapéutico , Infecciones por Salmonella/tratamiento farmacológico , Sepsis/tratamiento farmacológico , Adulto , Humanos , Masculino , Recurrencia , Infecciones por Salmonella/complicaciones , Salmonella typhimuriumRESUMEN
Motile curved bacilli seen in vaginal secretions have been isolated on Columbia agar supplemented with 5% human blood and vitamin K. Growth occurred both anaerobically and in 5% oxygen, but not under more aerobic conditions. There were two distinct groups of these organisms, distinguishable by morphology, biochemical activity, antigenic pattern and susceptibility to metronidazole. All isolates were sensitive to a wide range of antimicrobial agents, with the exception of nalidixic acid and polymyxin. One group was resistant to metronidazole.
Asunto(s)
Bacterias Anaerobias/aislamiento & purificación , Vaginitis/microbiología , Antibacterianos/farmacología , Bacterias Anaerobias/efectos de los fármacos , Bacterias Anaerobias/crecimiento & desarrollo , Femenino , Humanos , Pruebas de Sensibilidad MicrobianaRESUMEN
Motile curved rods seen in vaginal secretions have been isolated on Columbia agar supplemented with 5% human blood and vitamin K. Growth occurred anaerobically and in 5% oxygen but not in more aerobic conditions. There were two distinct groups of these organisms, distinguishable by morphology, biochemical activity and susceptibility to metronidazole. All isolates were sensitive to a wide range of antimicrobial agents, with the exception of nalidixic acid and polymyxin, but one group was resistant to metronidazole. There was little difference between the results of tests of susceptibility to aminoglycosides or to metronidazole performed in anaerobic and microaerophilic conditions. Motile curved rods were isolated from 18 of 80 patients with a clinical diagnosis of non-specific vaginitis, but from only two of 39 without the disease.
Asunto(s)
Bacterias/aislamiento & purificación , Leucorrea/microbiología , Vagina/microbiología , Antibacterianos/farmacología , Bacterias/citología , Fenómenos Fisiológicos Bacterianos , Femenino , Humanos , Metronidazol/farmacología , Pruebas de Sensibilidad Microbiana , Movimiento , Vagina/metabolismoRESUMEN
The efficacy of metronidazole in the treatment of acute dental infections was investigated and compared with parenteral penicillin in a controlled trial. All 37 patients in the trial responded satisfactorily and metronidazole appeared to be as effective as parenteral penicillin. A further 24 patients treated with metronidazole also responded satisfactorily. Bacteriological studies of pus obtained from 25 patients revealed the presence of many species of obligate anaerobes. Since metronidazole is only active against obligate anaerobic bacteria it is concluded that these organisms are the important pathogens in acute dental infections.