RESUMEN
Patent foramen ovale and hereditary thrombophilia are both known risk factors for ischemic stroke. Artery of Percheron is a rare anatomical variant in which vast areas of the midbrain and thalamus have a single source of blood supply. This case report presents a 45-years old female patient with bilateral thalamic stroke due to Percheron artery occlusion, with a combination of hereditary thrombophilia and patent foramen ovale as the risk factors. Modern approaches to the diagnosis and secondary prevention of this pathology are also discussed herein.
Asunto(s)
Foramen Oval Permeable , Accidente Cerebrovascular , Trombofilia , Femenino , Foramen Oval Permeable/complicaciones , Humanos , Persona de Mediana Edad , Factores de Riesgo , Accidente Cerebrovascular/complicaciones , Tálamo , Trombofilia/complicacionesRESUMEN
The aim was to study the efficacy of different groups of neuroleptics and antidepressants in the treatment of depression after stopping acute psychosis in schizophrenic patients. Authors observed 183 patients during the treatment using a psychopathological method and a battery of psychometric scales for assessing patient's state, structure of psychopathological syndrome and side-effects of the drugs. Correlation analysis was applied to compare treatment characteristics with the dynamics of disease course (favorable or less favorable) during 8 years. We used 13 antipsychotic drugs, including depot drugs, and 15 antidepressants. In conclusion, the additional and strictly differentiated prescription of antidepressants in the treatment of schizophrenic patients with depressive symptoms after stopping acute psychosis is effective and safe. It allows to improve quality of life and prognosis of patients.