RESUMEN
The objective was to determine the effect of supplementary feeding on the resilience and resistance of Criollo kids against natural gastrointestinal nematode (GIN) infections, when browsing native vegetation during the dry season in tropical Mexico. Thirty-three two-month-old Criollo kids, raised nematode free, were included at weaning in a 20-week trial. The kids were placed into four groups. Two groups of eight kids were offered 100g/day soybean and sorghum meal (26%:74% respectively fresh basis) (treated/supplemented (T-S) and infected/supplemented (I-S)). Two groups remained with no supplement for the duration of the trial (infected/non-supplemented (I-NS) (n=9) and treated/non-supplemented (T-NS) (n=8)). Kids in groups T-S and T-NS were drenched with 0.2mg of moxidectin/kg body weight orally (Cydectin, Fort Dodge) every 28 days. Groups I-S and I-NS were naturally infected with GIN. The animals browsed native vegetation for an average of 7h/day together with a herd of 120 naturally infected adult goats. Cumulative live weight gain (CLWG), packed cell volume (PCV), haemoglobin (Hb), total plasma protein and plasma albumin were recorded every 14 days as measurements of resilience. Resistance parameters (faecal egg counts (FEC) and peripheral eosinophil counts (PEC)) were also measured. Bulk faecal cultures were made for each group every 28 days. Every month a new pair of initially worm-free tracer kids assessed the infectivity of the vegetation browsed by the animals. Tracer kids and faecal cultures showed that kids faced low mixed infections (Haemonchus contortus, Trichostrongylus colubriformis and Oesophagostomum columbianum). Under conditions of scarce vegetation, such as those in the present study, supplemented groups (I-S and T-S) had higher growth rates compared to the non-supplemented groups independently of the control of GIN infection with anthelmintic (AH) treatment (P<0.001). Supplementary feeding did not affect FEC or PEC. In the absence of supplementation, lack of AH treatment may lead to outbreaks of clinical nematodosis. The supplementary feeding was economically feasible.
Asunto(s)
Fenómenos Fisiológicos Nutricionales de los Animales , Dieta/veterinaria , Enfermedades de las Cabras/inmunología , Parasitosis Intestinales/veterinaria , Infecciones por Strongylida/veterinaria , Animales , Antinematodos/uso terapéutico , Dieta/economía , Suplementos Dietéticos , Heces/parasitología , Enfermedades de las Cabras/parasitología , Enfermedades de las Cabras/prevención & control , Cabras , Hematócrito/veterinaria , Hemoglobinas/análisis , Interacciones Huésped-Parásitos , Parasitosis Intestinales/inmunología , Parasitosis Intestinales/prevención & control , Recuento de Leucocitos/veterinaria , Macrólidos/uso terapéutico , México , Nematodos/clasificación , Nematodos/aislamiento & purificación , Nematodos/patogenicidad , Recuento de Huevos de Parásitos/veterinaria , Estaciones del Año , Infecciones por Strongylida/inmunología , Infecciones por Strongylida/prevención & control , Aumento de Peso/fisiologíaRESUMEN
The objective was to determine the effect of supplementary feeding on the resilience and resistance of Criollo kids against natural gastrointestinal nematode (GIN) infections, when browsing native vegetation during the wet season in tropical Mexico. Thirty-four 2-month old Criollo kids, raised nematode free, were included at weaning in a 22-week trial. The kids were placed into four groups. Two groups of 8 kids were offered 100g/day soybean and sorghum meal (26%:74%, respectively fresh basis) (treated/supplemented (T-S) and infected/supplemented (I-S)). Two groups remained with no supplement for the duration of the trial (infected/non-supplemented (I-NS) (n = 10) and treated/non-supplemented (T-NS) (n = 8)). Kids in groups T-S and T-NS were drenched with 0.2mg of moxidectin/kg body weight orally (Cydectin, Fort Dodge) every 28 days. Groups I-S and I-NS were naturally infected with GIN. The animals browsed native vegetation (for an average of 7h/day) together with a herd of 120 naturally infected adult goats. Cumulative live weight gain (CLWG), packed cell volume (PCV), haemoglobin (Hb), total plasma protein and plasma albumin were recorded every 14 days as measurements of resilience. Resistance parameters (faecal egg counts (FEC) and peripheral eosinophil counts (PEC)) were also measured. Bulk faecal cultures were made for each group every 28 days. Every month a new pair of tracer kids assessed the infectivity of the vegetation browsed by the animals. The T-S group had the highest CLWG, PCV and Hb compared to the other three groups (P < 0.001). The I-S and T-NS group had similar mean CLWG and PCV (P > 0.05), while the I-NS group had the poorest CLWG, PCV and Hb (P < 0.001). The PEC of supplemented kids (I-S and T-S) was higher than in the I-NS and T-NS kids (P < 0.05). No effect of supplementary feeding was found in the FEC. Tracer kids and faecal cultures showed that kids suffered mixed infections with Haemonchus contortus, Trichostrongylus colubriformis and Oesophagostomum columbianum. Supplementary feeding improved resilience of browsing Criollo kids against natural GIN infections and was economically feasible. Improved resistance was also suggested by the PEC but was not confirmed in the FEC.
Asunto(s)
Alimentación Animal , Peso Corporal/efectos de los fármacos , Proteínas en la Dieta/administración & dosificación , Enfermedades de las Cabras/inmunología , Inmunidad Innata/fisiología , Infecciones por Nematodos/veterinaria , Alimentación Animal/economía , Animales , Análisis Costo-Beneficio , Suplementos Dietéticos , Heces/parasitología , Femenino , Enfermedades de las Cabras/sangre , Cabras , Masculino , México , Nematodos/crecimiento & desarrollo , Nematodos/patogenicidad , Infecciones por Nematodos/sangre , Infecciones por Nematodos/inmunología , Recuento de Huevos de Parásitos/veterinaria , Poaceae , Lluvia , Distribución Aleatoria , Estaciones del AñoAsunto(s)
Antiparasitarios/uso terapéutico , Enfermedades de los Gatos/tratamiento farmacológico , Dirofilariasis/tratamiento farmacológico , Enfermedades de los Perros/tratamiento farmacológico , Infestaciones Ectoparasitarias/veterinaria , Ivermectina/análogos & derivados , Animales , Antihelmínticos/administración & dosificación , Antihelmínticos/uso terapéutico , Antiparasitarios/administración & dosificación , Gatos , Dirofilaria immitis , Perros , Evaluación Preclínica de Medicamentos , Infestaciones Ectoparasitarias/tratamiento farmacológico , Femenino , Ivermectina/química , Ivermectina/uso terapéutico , Masculino , Ratones , Modelos Químicos , Siphonaptera/efectos de los fármacos , Infestaciones por Garrapatas/tratamiento farmacológico , Infestaciones por Garrapatas/veterinariaRESUMEN
Lungworm-infected seeder calves were used on four 1.41 ha paddocks to ensure that groups of 11 calves would be exposed to a heavy challenge with Dictyocaulus viviparus. By the 39th day after turnout there was a serious episode of respiratory disease and a diagnosis of parasitic bronchitis was confirmed by post mortem and faecal examination. One group of trial calves was treated with netobimin administered in the drinking water at 2.8 mg/kg/day for seven consecutive days; another group received the same treatment supplemented with flunixin meglumine at 2.2 mg/kg/day for three days; a third group was given a single oral dose of 7.5 mg netobimin/kg; only emergency treatments were given to calves in the control group. The clinical response to the drinking water treatments was highly satisfactory and better than the response to the single oral treatment.