Investigation of iodine nutritional status of children aged 8 to 10 years in Xiamen City from 2017 to 2019 / 中华地方病学杂志

Objective:To learn about the iodine nutritional status of children aged 8 to 10 years in Xiamen City after the reform of salt industry system, and to provide scientific basis for reasonable prevention and control of iodine deficiency disorders.Methods:From 2017 to 2019, 6 districts were selected each year in Xiamen City 5 sampling districts were divided according to the oriation of east, west, south, north and center in each district. One town (street, hereinafter refered as to town) was selected from each sampling district. One primary school was selected from each town. For each primary school, at least 40 non-boarding children aged 8 to 10 years (age balanced, half male and half female) were selected. Edible salt samples in the households and random urine samples of children aged 8 to 10 years were collected, and salt iodine and urinary iodine contents were measured, while thyroid volume was examined by B-ultrasound.Results:From 2017 to 2019, the coverage rate of iodized salt in Xiamen City was 97.34% (1 206/1 239), 96.89% (1 214/1 253), and 93.33% (1 175/1 259), respectively; the consumption rate of qualified iodized salt was 96.13% (1 191/1 239), 95.61% (1 198/1 253), and 91.58% (1 153/1 259), respectively; the median urinary iodine was 182.90, 182.81, 164.00 μg/L, respectively. The prevalence of goiter of boys and girls was 1.01% (19/1 889) and 2.26% (42/1 862), respectively.Conclusions:After the reform of salt industry system, the iodine nutritional status of children aged 8 to 10 years is generally at an appropriate level in Xiamen City. However, the consumption rate of qualified iodized salt is reduced, which increases the risk of iodine deficiency for residents. Therefore, we should strengthen the propaganda of scientific iodine supplement, maintain a high consumption rate of qualified iodized salt, and prevent the harm of iodine deficiency.

Ginger-indirect moxibustion plus acupuncture versus acupuncture alone for chronic fatigue syndrome: a randomized controlled trial.

OBJECTIVE: To assess the efficacy and safety of ginger-indirect moxibustion for chronic fatigue syndrome (CFS). METHODS: In this central randomized, controlled trial, 290 CFS participants were recruited and randomly allocated to group A (ginger-indirect moxibustion plus acupuncture) or group B (acupuncture alone). The study consisted of a treatment period of 8 weeks with a total of 24 treatments (3 sessions per week, every other day), and a follow-up period of 12 weeks. The outcome was measured by Fatigue Severity Scale (FSS), Psychological Health Report (SPHERE), the Self-rating depression scale (SDS) and the Hamilton anxiety scale (HAMA) at baseline, 2, 4, 6, 8, 12 and 20 weeks. RESULTS: With the treatment undergoing, the changes of FSS, SPHERE, SDS and HAMA scores in both groups increased gradually, and the effect maintained at the 12th week. Between groups, significantly higher score changes were seen in group A in FSS after 4 weeks treatment (11.94 9.12, 95%: 0.94, 4.7) and in SPHERE after 2 weeks treatment (3.7 2.27, 95%: 0.56, 2.31). But for SDS and HAMA, the improvement did not differ significantly between groups. No severe adverse events were reported. CONCLUSION: Ginger-indirect moxibustion is a safe and effective intervention to relieve fatigue and accompanying physical symptoms of CFS.

Study on the effect of Traditional Chinese Medicine psychological sleep regulation technology on insomnia with deficiency of heart and gallbladder qi / 国际中医中药杂志

Objective:We study the clinical effect of (Traditional Chinese Medicine) TCM psychological sleep regulation technique in treating insomnia with deficiency of heart and gallbladder qi.Methods:A total of 60 patients from the Sleep Medicine Special Outpatient Department of Guang’anmen Hospital of China Academy of Chinese Medical Sciences, who met the inclusion criteria from June 2020 to March 2021, were divided into 2 groups with 30 in each group, by random number table method. The treatment group were treated with TCM psychological sleep regulation technology. The control group were treated with Zopiclone tablets for 4 weeks. We used the Insomnia Severity Index (ISI) to assess the severity of insomnia, the self-developed TCM syndrome to assess the severity of symptoms, and the Dysfunctional Beliefs and Attitudes Scale to assess the unreasonable cognition related to sleep before and after treatment. The Treatment Emergent Symptom Scale (TESS) was used to assess the safety of the 2 groups in the 4th week of treatment.Results:The total effective rate was 77.7% (23/30) in the treatment group and 80.0% (24/30) in the control group. There was no significant difference between the two groups ( χ2=0.098, P=0.754). After treatment, the score of TCM syndromes in the treatment group (5.15 ± 2.66 vs. 8.98 ± 2.05, t=-1.552) was significantly lower than that of the control group ( P<0.05), and the DBAS-30 score (125.84 ± 20.57 vs. 82.89 ± 21.64, t=2.445) was significantly higher than that of the control group ( P<0.05). Conclusions:TCM psychological sleep control technology can improve the clinical symptoms of patients with insomnia, and heart and gallbladder qi deficiency. The efficacy is similar to that of Zopiclone, and it is superior to western medicine in improving beliefs and attitudes of sleep.

Shenmai injection protects mitochondria from oxidative injury in myocardial cells and its mechanism / 浙江大学学报·医学版

OBJECTIVE@#To investigate the effect of Shenmai injection on myocardial cells with oxidative injury and the underlying mechanisms.@*METHODS@#Tert-butyl hydroperoxide (t-BHP) was used to induce the oxidative stress in H9c2 myocardial cells. The cell viability and ATP level were evaluated using MTT-colorimetric method and CellTiter-Glo luminescent cell viability assay. The oxygen respiration rate was examined by Clark oxygen electrode. Pyruvate and pyruvate dehydrogenase (PDH) levels were evaluated by ELISA kit. Western blot and quantitative real-time RT-PCR were employed to evaluate the expression of pyruvate dehydrogenase alpha 1(PDHA1) and pyruvate dehydrogenase kinase 1(PDK1).@*RESULTS@#Shenmai injection significantly improved viability and respiration of H9c2 myocardial cells after t-BHP injury (0.05).@*CONCLUSIONS@#Shenmai injection protects mitochondria from oxidative stress by increasing PDH level, which indicates that it may improve energy metabolism of myocardial cells.

The similarities and differences between thought imprint psychotherapy under hypnosis and narrative therapy / 国际中医中药杂志

Thought Imprint Psychotherapy under Hypnosis(TIP)and Narrative Therapy are two different kinds of psychotherapy, both with the characteristic of story treatment. The psychotherapist uses re-growth means in TIP treatment, and Narrative Therapy uses means such as externalizing problems, reconstructing story, and so on. This article chiefly discusses two treatments, to confirm some similarities and differences between them and provide guidance for the actual treatment.

The influence of vagus nerve stimulation on NMDAR1 mRNA and GABAAR alpha 1 mRNA in thalamic reticular neucus of pentylenetetrazole-induced epileptic rats / 生物医学工程学杂志

To study the antiepileptic mechanism of vagus nerve stimulation (VNS), we used the methods of in situ hybridyzation and image analysis to detect the expression of NMDAR1 mRNA and GABAA receptor alpha 1 subunit mRNA (GABAAR alpha 1 mRNA) in the thalamic reticular nuclus. The results show that the NMDAR1 mRNA expression of rats administered pentylenetetrazole(PTZ) is higher than that of control group. By treating with VNS, it decreased. On the contrary, the expression of GABAAR alpha 1 mRNA in the thalamic reticular nuclus of PTZ group rats is lower than that of control group. For rats treated with VNS, it increased. Therefore, it is concluded that VNS may reduce the excitability of cerebral cortices by depressing the activities of glutamic acid receptors (GluR) and by promoting the activities of gamma-aminobutyric acid receptors(GABAR) in thalamic reticular nuclus. So the formation and development of seizures are inhibited.