1.
Arch Geschwulstforsch
; 49(1): 15-7, 1979.
Artículo
en Alemán
| MEDLINE
| ID: mdl-444028
RESUMEN
Eight of fifteen Fluorenone-Azomethines without alkylating function have been found effective against the leukemia L 1210. Little modifications concerning the structure of the compounds caused loss of effectiveness. It seems remarkably that one corresponding derivative with a nitrogen mustard group (4) was ineffective. Correlations between chemical structure and biological effect have not yet been found.
Asunto(s)
Antineoplásicos/uso terapéutico , Fluorenos/uso terapéutico , Leucemia L1210/tratamiento farmacológico , Animales , Evaluación Preclínica de Medicamentos , Femenino , Masculino , Ratones , Ratones Endogámicos A , Ratones Endogámicos DBA , Relación Estructura-Actividad
2.
Pharmazie
; 30(7): 433-5, 1975 Jul.
Artículo
en Alemán
| MEDLINE
| ID: mdl-1178756