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Métodos Terapéuticos y Terapias MTCI
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1.
Pak J Pharm Sci ; 29(5): 1541-1544, 2016 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-27731810

RESUMEN

The present study demonstrates the biological study of Ficus carica fruit. Methanolic extract of plant fruit was prepared and evaporated under reduced pressure by rota vapor and n- hexane, Chloroform, ethyl acetate and n-butanol soluble fractions were prepared separately from crude methanolic extract. These fractions were then screened for acetyl cholinesterase, butryl cholinesterase and lipoxygenase activities. n-butanol soluble fraction showed significant antiacetylcholinesterase activity (78.55±0.76%) with IC50 of 55.8±0.37µg/ml, ethyl acetate soluble fraction showed significant anti-butrylcholinesterase activity (70.35±0.85%) with IC50 of 276.5±0.64µg/ml and significant antilipoxygenase activity was shown by ethyl acetate soluble fraction (62.52±0.26%) with IC50 of 380±0.08µg/ml.


Asunto(s)
Inhibidores de la Colinesterasa/farmacología , Ficus/química , Inhibidores de la Lipooxigenasa/farmacología , Fraccionamiento Químico , Inhibidores de la Colinesterasa/aislamiento & purificación , Frutas , Inhibidores de la Lipooxigenasa/aislamiento & purificación , Fitoterapia , Plantas Medicinales , Solventes/química
2.
Pak J Pharm Sci ; 27(5): 1209-13, 2014 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-25176377

RESUMEN

The present study demonstrates the biological activity of Ochthochloa compressa, since extensive literature survey has shown no documented biological activity of this plant. Ethanolic extract of whole plant was prepared and evaporated under reduced pressure by rota vapor. The crude extract was further fractionated into n-hexane, dichloromethane, ethyl acetate and n-butanol soluble fractions. These fractions were screened for antifungal, phytotoxic, cytotoxic and antibacterial activities. Dichloromethane soluble fraction showed significant phytotoxicity whereas n-hexane, ethyl acetate, and n-butanol soluble fractions showed non-significant phytotoxicity. Similarly, ethyl acetate soluble fraction was the only fraction, which showed significant cytotoxic activity. There was no antibacterial but moderate antifungal activity was shown by these fractions against selected strains of bacteria and fungi. This is the first report on the biological activity of O. compressa.


Asunto(s)
Antiinfecciosos/farmacología , Extractos Vegetales/farmacología , Poaceae
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