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1.
ACS Appl Mater Interfaces ; 16(7): 9020-9029, 2024 Feb 21.
Artículo en Inglés | MEDLINE | ID: mdl-38324755

RESUMEN

Despite the considerable potential of AlGaN-based ultraviolet-B light-emitting diodes (UV-B LEDs) in various applications such as phototherapy, UV curing, plant growth, and analytical technology, their development is still ongoing due to low luminescence efficiency. In this study, we introduced a novel epitaxial growth mechanism to effectively control the height and thickness of AlGaN multiple wells (MWs) on AlGaN nanorod structures using horizontal reactor-based metal-organic chemical vapor deposition (MOCVD). By adjusting the H2 carrier gas flow rate, we could control the growth boundary layer's thickness, successfully separating the AlGaN well and p-AlGaN layer from the substrate. Cathodoluminescence (CL) measurements confirmed the stability of the core-shell AlGaN quantum wells as a highly stable nonpolarized structure, with the wavelength peak remaining almost unchanged under various injection currents. Furthermore, transmission electron microscopy (TEM) provided clear evidence of differentiation, highlighting the distinct formation of the 275 nm AlGaN core and the 295 nm AlGaN shell structure. The developed AlGaN MW structure, characterized by these rectification features, not only demonstrated a significantly improved electroluminescence (EL) peak intensity but also exhibited a much lower leakage current compared to the conventional core-shell AlGaN structure. The newly proposed growth mechanism and advanced nonpolarized core-shell AlGaN structure are expected to serve as excellent alternatives for substantially enhancing the efficiency of the next generation of high-efficiency UV LEDs.

2.
J Neurol Sci ; 337(1-2): 243-4, 2014 Feb 15.
Artículo en Inglés | MEDLINE | ID: mdl-24368013

RESUMEN

Dizziness and ataxia are known adverse effects of pregabalin, but characteristic oculomotor signs in pregabalin intoxication have not been reported. Here we describe a patient who displayed perverted head-shaking and positional downbeat nystagmus after prescription of a high dosage of pregabalin. Since pregabalin reduces excitatory neurotransmitter secretion in the central nervous system, decreased excitatory inputs from the brainstem may lead to cerebellar dysfunction, causing perverted head-shaking and positional downbeat nystagmus.


Asunto(s)
Movimientos de la Cabeza/efectos de los fármacos , Nistagmo Patológico/inducido químicamente , Temblor/inducido químicamente , Ácido gamma-Aminobutírico/análogos & derivados , Aciclovir/uso terapéutico , Anciano , Anticonvulsivantes/efectos adversos , Anticonvulsivantes/farmacología , Antivirales/uso terapéutico , Mareo , Femenino , Humanos , Pregabalina , Vértigo , Ácido gamma-Aminobutírico/efectos adversos , Ácido gamma-Aminobutírico/farmacología
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