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Eur J Cancer ; 135: 103-112, 2020 08.
Artículo en Inglés | MEDLINE | ID: mdl-32563014

RESUMEN

Malignant dysphagia is the most common symptom in advanced oesogastric cancers patients. Relief of dysphagia allows quality of life improvement, nutritional replenishment and potentially improves prognosis. Chemotherapy alone is effective and should be prioritised in patients with metastatic disease a good performance status, and its impact on dysphagia should be determined before further interventions are planned. Regarding local treatments, the insertion of a covered self-expandable metallic stent is the most commonly used alternative, as it allows for the rapid relief of severe dysphagia. Although several randomised trials have highlighted the role of oesophageal brachytherapy, this technique is often not easily accessible. Contemporary trials are ongoing to better define the role of external radiation therapy. While awaiting these results, external radiation therapy can be considered as a second-best option for patients with a life-expectancy > 3 months. It is important to offer nutritional support and to integrate quality of life measures in the palliative management of dysphagia. This multidisciplinary international position paper aims to propose a decision-making process and highlight randomised trials for the management of malignant dysphagia in metastatic oesogastric cancer patients.


Asunto(s)
Antineoplásicos/uso terapéutico , Trastornos de Deglución/terapia , Deglución , Neoplasias Esofágicas/tratamiento farmacológico , Cuidados Paliativos , Braquiterapia , Consenso , Trastornos de Deglución/etiología , Trastornos de Deglución/fisiopatología , Neoplasias Esofágicas/complicaciones , Neoplasias Esofágicas/patología , Humanos , Metástasis de la Neoplasia , Apoyo Nutricional , Calidad de Vida , Recuperación de la Función , Stents Metálicos Autoexpandibles , Resultado del Tratamiento
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