Asunto(s)
Antiparkinsonianos/farmacología , Escarabajos , Intoxicación por MPTP/tratamiento farmacológico , Animales , Antiparkinsonianos/aislamiento & purificación , Biopelículas , Terapia Biológica , Peso Corporal/efectos de los fármacos , Fibras de la Dieta , Enterococcus , Ácido Láctico , Leuconostoc , Locomoción/efectos de los fármacos , Intoxicación por MPTP/patología , Intoxicación por MPTP/fisiopatología , Masculino , Ratones Endogámicos C57BL , Microscopía Electrónica de Rastreo , Leche , Porción Compacta de la Sustancia Negra/efectos de los fármacos , Porción Compacta de la Sustancia Negra/metabolismo , Porción Compacta de la Sustancia Negra/patología , Prueba de Desempeño de Rotación con Aceleración Constante , Tirosina 3-Monooxigenasa/metabolismoRESUMEN
It was shown that the association of probiotic bacteria of the genuses Bacillus and Cellulomonas form biolayers on the surface of beet marc particles. The positive effect of a fodder additive that contained the biolayer on the basis of a phytomatrix on the growth and development of young rabbits was shown. Feeding of animals with a mixed fodder that contained 0.1% preparation resulted in stimulation of digestion of all components of the food. Among other components of the mixed fodder, cellulose was digested most effectively. An increase in the biomass of symbiotic bacteria and enzymatic activity in the blindgut chymus was also observed. The positive nitrogen balance demonstrated an increase in the nitrogen content in animals and a decrease of its losses with excretion. The mechanism of response of the rabbit's organism to introduction of the complex probiotic preparation into the digestive tract is discussed.