RESUMEN
From the water-soluble fraction of the dried leaves of Alangium chinense, three new glycosides, benzyl alcohol beta-D-glucopyranosyl-(1 --> 2)-[beta-D-xylopyranosyl-(1 --> 6)]-beta-D-glucopyranoside, 2'-O-beta-D-glucopyranosylsalicin, and 2'-O-beta-D-glucopyranosyl-6'-O-beta-D-xylopyranosylsalicin were isolated along with seven known glycosides. The structures of the new compounds were determined by spectroscopic and chemical means.
Asunto(s)
Alcoholes Bencílicos/química , Cornaceae/química , Plantas Medicinales/química , China , Glicósidos/química , Glicósidos/aislamiento & purificación , Hidrólisis , Espectroscopía de Resonancia Magnética , Hojas de la Planta/química , Espectrofotometría Infrarroja , Espectrofotometría UltravioletaRESUMEN
From the leaves of Alangium kurzii, a new tetrahydroisoquinoline-monoterpene glucoside, 6-O-methyl-N-deacetylipecosidic acid and a new iridoid glucoside, 10-O-benzoyladoxosidic acid, were isolated along with alangiside, demethylalangiside, 6''-O-beta-D-glucosylhenryoside, uridine and four known flavonoid glycosides. The structures of new glucosides were determined on the basis of spectroscopic and chemical methods.
Asunto(s)
Isoquinolinas/aislamiento & purificación , Plantas Medicinales/química , Terpenos/aislamiento & purificación , Acetilación , Catálisis , China , Flavonoides/aislamiento & purificación , Glicósidos/aislamiento & purificación , Espectroscopía de Resonancia Magnética , Metilación , Espectrofotometría Infrarroja , Espectrofotometría UltravioletaRESUMEN
From the dried leaves of Alangium chinense, five novel phenolic glycosides, 6'-O-galloylsalicin (1); 4',6'-di-O-galloylsalicin (2); 4',6'-O-(S)-hexahydroxydiphenoylsalicin (3); 4', 6'-O-(R)-hexahydroxydiphenoylsalicin (4); and pyrocatechol 1-O-beta-D-xylopyranosyl(1-->6)-beta-D-glucopyranoside (5) were isolated. The structures of these new compounds were determined by spectroscopic methods.
Asunto(s)
Glicósidos/aislamiento & purificación , Fenoles/química , Plantas Medicinales/química , Conformación de Carbohidratos , Glicósidos/química , Espectroscopía de Resonancia Magnética , Espectrometría de MasasRESUMEN
As a continuing study of chemical characterization of crude drug processing, we have been analyzing the chemical constituents in licorice roots before and after processing. At first, we analyzed chemical constituents in licorice roots of various origins. Next, we have developed the HPLC analytical method, by which saponins and flavonoids, major constituents in various licorice roots, were determined simultaneously in a quantitative manner. In this paper, by means of the HPLC analytical method, chemical constituents in licorice roots, processed and unprocessed, were determined. It was found that nonglycosidic flavonoid constituents were mostly lost while root bark removing, whereas, in roasted licorice roots, sugar chains in the saponin and glycosidic flavonoid constituents were hydrolyzed stepwise during roasting through hydrothermolysis.
Asunto(s)
Flavonoides/análisis , Glycyrrhiza/química , Plantas Medicinales , Saponinas/análisis , Cromatografía Líquida de Alta Presión/métodos , Composición de Medicamentos , Calor , HidrólisisAsunto(s)
Inhibidores Enzimáticos/farmacología , Ácido Gálico/análogos & derivados , Glucosa/análogos & derivados , Taninos Hidrolizables , Monofenol Monooxigenasa/antagonistas & inhibidores , Plantas Medicinales/química , Taninos/farmacología , Ácido Gálico/aislamiento & purificación , Ácido Gálico/farmacología , Glucosa/aislamiento & purificación , Glucosa/farmacología , Hidroquinonas/aislamiento & purificación , Hidroquinonas/farmacología , Extractos Vegetales/química , Taninos/aislamiento & purificaciónRESUMEN
A new acetophenone glycoside, affinoside, was isolated from the aerial parts of Exacum affine and its structure was determined as 2-O-primeverosylpaenol. The known glucosides, gentiopicroside, 2'-O-E/Z-p-coumaroylloganin and glucopaeonol, were also identified.