Asunto(s)
Hipertermia Inducida , Neoplasias de los Tejidos Blandos/terapia , Terapia Combinada , Estudios de Evaluación como Asunto , Humanos , Microondas , Recurrencia Local de Neoplasia/radioterapia , Recurrencia Local de Neoplasia/terapia , Cuidados Paliativos , Neoplasias de los Tejidos Blandos/radioterapia , Neoplasias de los Tejidos Blandos/secundarioRESUMEN
Undifferentiated giant and spindle cell carcinoma is an unusual and high-grade malignant type of cancer of the thyroid. The results of surgical and/or radiotherapeutic treatment have been discouraging. Only a few patients respond to therapy, usually for a short time. Recently, a few reports have been published on the effect of chemotherapy or a combined treatment of surgery, radiotherapy and chemotherapy. In the present paper the results of combining radiotherapy and chemotherapy, 5-FU and cyclophosphamide, are reported. For the future a more aggressive approach is discussed. The therapy should include surgical resection of the main bulk of the tumour, followed by radiotherapy and concomitant chemotherapy and thereafter prolonged adjuvant chemotherapy.