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1.
J Ethnopharmacol ; 111(2): 197-201, 2007 May 04.
Artículo en Inglés | MEDLINE | ID: mdl-17210236

RESUMEN

Essential oils obtained from leaves of 29 medicinal plants commonly used in Brazil were screened against 13 different Escherichia coli serotypes. The oils were obtained by water-distillation using a Clevenger-type system and their minimal inhibitory concentration (MIC) were determined by microdilution method. Essential oil from Cymbopogon martinii exhibited a broad inhibition spectrum, presenting strong activity (MIC between 100 and 500 microg/mL) against 10 out of 13 Escherichia coli serotypes: three enterotoxigenic, two enteropathogenic, three enteroinvasive and two shiga-toxin producers. C. winterianus inhibited strongly two enterotoxigenic, one enteropathogenic, one enteroinvasive and one shiga-toxin producer serotypes. Aloysia triphylla also shows good potential to kill Escherichia coli with moderate to strong inhibition. Other essential oils showed antimicrobial properties, however with a more restricted action against the serotypes studied. Chemical analysis of Cymbopogon martinii essential oil performed by gas chromatography (GC) and gas chromatography/mass spectrometry (GC-MS) showed the presence of compounds with known antimicrobial activity, including geraniol, geranyl acetate and trans-cariophyllene, which tested separately, indicated geraniol as antimicrobial active compound. The significant antibacterial activity of Cymbopogon martinii oil suggests that they could serve as a source for compounds with therapeutic potential.


Asunto(s)
Antiinfecciosos/farmacología , Cymbopogon/química , Escherichia coli/efectos de los fármacos , Etnofarmacología , Medicina Tradicional , Aceites Volátiles/farmacología , Aceites de Plantas/farmacología , Plantas Medicinales/química , Acetatos/química , Acetatos/farmacología , Monoterpenos Acíclicos , Antiinfecciosos/análisis , Antiinfecciosos/aislamiento & purificación , Brasil , Cromatografía de Gases , Cymbopogon/anatomía & histología , Escherichia coli/clasificación , Escherichia coli/patogenicidad , Cromatografía de Gases y Espectrometría de Masas , Pruebas de Sensibilidad Microbiana , Aceites Volátiles/análisis , Aceites Volátiles/aislamiento & purificación , Hojas de la Planta/química , Aceites de Plantas/análisis , Aceites de Plantas/aislamiento & purificación , Serotipificación , Terpenos/química , Terpenos/farmacología
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