[Aminostigmine as a cholinesterase inhibitor and as an agent for treating poisonings by cholinergic blockers]. / Aminostigmin kak ingibitor kholinésterazy i kak sredstvo dlia lecheniia otravlenii kholinoblokatorami.

Experiments on non-inbred albino mice have demonstrated that aminostigmine is an active reversible centrally active cholinesterase inhibitor close to the properties of physostigmine, but greatly superior to it in its action duration. Clinical examinations of healthy volunteers and patients have shown that aminostigmine-induced inhibition of cholinesterase activity persists 6 hours. The agent have been found to be more highly effective in treating cholin blocker-induced intoxications than galanthamine, which manifests itself in its greater stability of the therapeutical effect achieved and in its higher ability to prevent cardiovascular events occurring in intoxication.

[Basic principles and trends in the intensive therapy of severe forms of alcoholic delirium]. / Osnovnye printsipy i napravleniia intensivnoi terapii tiazhelykh form alkogol'nogo deliriia

The paper presents therapeutical results of 105 patients with severe forms of alcoholic delirium who were treated by intensive therapeutical methods in a specialized department. The main trends of the intensive therapy were the following: discontinuation of psychomotor excitation and general hyperkinesia, the treatment of respiration disturbances and massive infusion therapy. As a result, in 87 patients of 105 the psychotic condition was ceasted 12--24 hours after the beginning of the treatment.