RESUMEN
Laughing gas (Nitrogen monoxide) is currently abused due to its low price and easy availability. This article discussed the clinical manifestations of a patient with subacute combined degeneration of the spinal cord caused by inhalation of laughing gas. The patient developed numbness of extremities, unstable walking, and decreased serum vitamin B(12) level. MRI of the cervical spine showed abnormal signals in the lateral and posterior cords of the cervical spinal cord (C2-6) , neuroelectrophysiological examination showed peripheral nerve damage in the extremities. After treatment with vitamin B(12) supplementation, the patient's condition gradually improved. Clinicians diagnose subacute combined degeneration of the spinal cord, especially when the patient has no gastrointestinal disease, diet, malnutrition, etc., they need to carefully inquire about the history of nitrous oxide inhalation to avoid missed diagnosis.
Asunto(s)
Óxido Nitroso , Degeneración Combinada Subaguda , Vértebras Cervicales , Humanos , Imagen por Resonancia Magnética , Óxido Nitroso/efectos adversos , Médula Espinal , Degeneración Combinada Subaguda/inducido químicamente , Vitamina B 12RESUMEN
OBJECTIVE: To search for new effective ant-early-pregnancy components from the aerial part of Verbena officinalis. METHOD: Compounds were isolated from the methanol extract of the herb by chromatography on silica gel column, and the structures were determined by physical and chemical evidences and spectroscopic analysis. RESULT: Two compounds were obtained and identified as 3,4-dihydroverbenalin and daucosterol. CONCLUSION: The two compounds were obtained from this the herb for the first time and 3,4-didydroverbenalin is a new product.
Asunto(s)
Compuestos Heterocíclicos con 2 Anillos/aislamiento & purificación , Plantas Medicinales/química , Verbena/química , Compuestos Heterocíclicos con 2 Anillos/química , Estructura Molecular , Tallos de la Planta/química , Sitoesteroles/química , Sitoesteroles/aislamiento & purificaciónRESUMEN
The relationship between maternal hematocrit and pregnancy outcome at various times in pregnancy was studied in 17,149 iron- and folate-supplemented pregnant women. On univariate analysis, early-pregnancy hematocrits below 37% were associated with preterm delivery. However, this relationship was not confirmed by multivariate analysis controlling for other risk factors. On both univariate and multivariate analyses, both early and later in pregnancy, hematocrits above 40% were associated with preterm delivery. In every gestational time period, at least part of the excess of preterm births was explained by an increase in indicated preterm deliveries. In both early and late pregnancy, and in both the univariate and multivariate analyses, only high hematocrits were associated with fetal growth retardation. The strongest association (odds ratio above 2) between high hematocrit and both fetal growth retardation and preterm delivery occurred with hematocrits at or above 43% at 31-34 weeks' gestation.