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1.
Biomolecules ; 10(1)2020 01 06.
Artículo en Inglés | MEDLINE | ID: mdl-31935798

RESUMEN

In the present study, economically viable NiO nanoparticles were produced by biogenic preparation using stevia leaf broth and their in-vitro antioxidant and antimicrobial activities were evaluated. The properties of the prepared NiO nanoparticles were confirmed by analytical techniques such as Ultraviolet-Visible (UV-Vis), X-ray diffraction (XRD), FE-SEM, and Fourier transform infrared spectroscopy (FTIR) analyses. Morphological studies using scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed that the size of synthesized nanoparticles ranged from 20 to 50 nm, most of which were spherical and few of which were agglomerated. The role of the biological moieties, which reduce and cap the nanoparticles, was studied using FTIR analysis. The prepared nanoparticles strongly inhibited gram-negative bacteria, which is a camper with gram-positive bacteria and fungi. Furthermore, it performs an effective in-vitro activity through α,α-diphenyl-ß-picrylhydrazyl (DPPH) reduction. Thus, it can be concluded that the effective and easy green synthesis process used for NiO nanoparticles provides potential antimicrobial agents against multidrug-resistant microbes.


Asunto(s)
Nanopartículas del Metal/química , Extractos Vegetales/farmacología , Stevia/metabolismo , Antibacterianos/farmacología , Antiinfecciosos/farmacología , Antioxidantes/farmacología , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Tecnología Química Verde/métodos , Pruebas de Sensibilidad Microbiana , Microscopía Electrónica de Transmisión/métodos , Níquel/química , Tamaño de la Partícula , Extractos Vegetales/química , Hojas de la Planta/metabolismo , Espectroscopía Infrarroja por Transformada de Fourier/métodos , Stevia/química , Difracción de Rayos X/métodos
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