A half jaw panoramic stitching method of intraoral endoscopy images based on dental arch arrangement.

To address the challenges of repetitive and low-texture features in intraoral endoscopic images, a novel methodology for stitching panoramic half jaw images of the oral cavity is proposed. Initially, an enhanced self-attention mechanism guided by Time-Weighting concepts is employed to augment the clustering potential of feature points, thereby increasing the number of matched features. Subsequently, a combination of the Sinkhorn algorithm and Random Sample Consensus (RANSAC) is utilized to maximize the count of matched feature pairs, accurately remove outliers and minimize error. Last, to address the unique spatial alignment among intraoral endoscopic images, a wavelet transform and weighted fusion algorithm based on dental arch arrangement in intraoral endoscopic images have been developed, specifically for use in the fusion stage of intraoral endoscopic images. This enables the local oral images to be precisely positioned along the dental arch, and seamless stitching is achieved through wavelet transformation and a gradual weighted fusion technique. Experimental results demonstrate that this method yields promising outcomes in panoramic stitching tasks for intraoral endoscopic images, achieving a matching accuracy of 84.6% and a recall rate of 78.4% in a dataset with an average overlap of 35%. A novel solution for panoramic stitching of intraoral endoscopic images is provided by this method.

The Herbal Combination of Radix astragali, Radix angelicae sinensis, and Caulis lonicerae Regulates the Functions of Type 2 Innate Lymphocytes and Macrophages Contributing to the Resolution of Collagen-Induced Arthritis.

Type 2 innate lymphocytes (ILC2s), promoting inflammation resolution, was a potential target for rheumatoid arthritis (RA) treatment. Our previous studies confirmed that R. astragali and R. angelicae sinensis could intervene in immunologic balance of T lymphocytes. C. lonicerae also have anti-inflammatory therapeutic effects. In this study, the possible molecular mechanisms of the combination of these three herbs for the functions of ILC2s and macrophages contributing to the resolution of collagen-induced arthritis (CIA) were studied. Therefore, we used R. astragali, R. angelicae sinensis, and C. lonicerae as treatment. The synovial inflammation and articular cartilage destruction were alleviated after herbal treatment. The percentages of ILC2s and Tregs increased significantly. The differentiation of Th17 cells and the secretion of IL-17 and IFN-γ significantly decreased. In addition, treatment by the combination of these three herbs could increase the level of anti-inflammatory cytokine IL-4 secreted, active the STAT6 signaling pathway, and then contribute to the transformation of M1 macrophages to M2 phenotype. The combination of the three herbs could promote inflammation resolution of synovial tissue by regulating ILC2s immune response network. The synergistic effects of three drugs were superior to the combination of R. astragali and R. angelicae sinensis or C. lonicerae alone.