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Gan To Kagaku Ryoho ; 49(10): 1121-1124, 2022 Oct.
Artículo en Japonés | MEDLINE | ID: mdl-36281607

RESUMEN

Respiratory symptoms are rarely reported as side effects of oxaliplatin, 5-fluorouracil, and Leucovorin(FOLFOX)therapy. We report a case of a patient with FOLFOX-induced unilateral interstitial pneumonia. The patient was a 68-year-old man who underwent ileocecal resection of cecum cancer. FOLFOX regimen was started as an adjuvant chemotherapy. After the administration of 11 courses, he visited our hospital with fever, dyspnea, and anorexia. We diagnosed this as FOLFOX- induced unilateral interstitial pneumonia through a blood test, chest radiograph, computed tomography, and bronchoscopy. Treatment was started with 30 mg of prednisolone, and the dosage was gradually decreased. The patient responded well to the treatment and was discharged from the hospital without any complications on the 33th day after admission.


Asunto(s)
Neoplasias Colorrectales , Enfermedades Pulmonares Intersticiales , Masculino , Humanos , Anciano , Leucovorina/efectos adversos , Oxaliplatino/efectos adversos , Fluorouracilo/efectos adversos , Protocolos de Quimioterapia Combinada Antineoplásica/efectos adversos , Enfermedades Pulmonares Intersticiales/inducido químicamente , Enfermedades Pulmonares Intersticiales/tratamiento farmacológico , Enfermedades Pulmonares Intersticiales/cirugía , Prednisolona/efectos adversos , Neoplasias Colorrectales/tratamiento farmacológico
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