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Métodos Terapéuticos y Terapias MTCI
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1.
Foot (Edinb) ; 34: 40-44, 2018 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-29278835

RESUMEN

BACKGROUND: Chronic osteomyelitis necessities appropriate infected bone and soft tissue excision. The authors describe the Silo surgical technique for the treatment of calcaneal osteomyelitis using a new antibiotic-loaded absorbable calcium sulphate/hydroxyapatite biocomposite. METHODS: The Silo method involves debridement of the dead bone and local delivery of antibiotic in drilled tunnels using the biocomposite. It is combined with multiple sampling and culture-specific systemic antibiotic treatment guided by a multidisciplinary team. Twelve consecutive diabetic patients with heel ulcers and calcaneal osteomyelitis were treated with the above method. All had comorbidities (Cierny-Mader (C-M) Class B hosts). The mean age was 68 years (range 50-85). A retrospective review of radiographs and electronic medical records was conducted. RESULTS: Patients were followed up until clinical cure of the ulcer for a mean of 16 weeks (range 12-18). Infection was eradicated in all 12 patients with a single stage procedure following a bone preserving technique. One patient required a subsequent flap operation and six vacuum-assisted closure (V.A.C.). There was also one case of prolonged wound leakage and no calcaneal fractures. CONCLUSIONS: The Silo technique is an effective method of local delivery of antibiotics and can be effectively implemented into the single-stage treatment of calcaneal osteomyelitis offering increased bone preservation and local delivery of antibiotic, decreasing the need for a major amputation. LEVEL OF EVIDENCE: Level IV- case series.


Asunto(s)
Sulfato de Calcio/farmacología , Pie Diabético/cirugía , Gentamicinas/farmacología , Osteomielitis/cirugía , Colgajos Quirúrgicos/trasplante , Implantes Absorbibles , Anciano , Anciano de 80 o más Años , Calcáneo/patología , Calcáneo/cirugía , Enfermedad Crónica , Terapia Combinada , Bases de Datos Factuales , Desbridamiento/métodos , Pie Diabético/diagnóstico por imagen , Pie Diabético/tratamiento farmacológico , Sistemas de Liberación de Medicamentos , Durapatita/farmacología , Femenino , Humanos , Imagen por Resonancia Magnética/métodos , Masculino , Persona de Mediana Edad , Osteomielitis/diagnóstico por imagen , Osteomielitis/tratamiento farmacológico , Radiografía/métodos , Estudios Retrospectivos , Resultado del Tratamiento , Cicatrización de Heridas/fisiología
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