RESUMEN
OBJECTIVES: To assess the effects of mindfulness-based relapse prevention for alcohol dependence (MBRP-A) intervention on drinking and related consequences. METHODS: 123 alcohol-dependent adults in early recovery, recruited from outpatient treatment programs, were randomly assigned to MBRP-A (intervention plus usual-care; Nâ¯=â¯64) or Control (usual-care-alone; Nâ¯=â¯59) group. MBRP-A consisted of eight-weekly sessions and home practice. Outcomes were assessed at baseline, 8â¯weeks and 26â¯weeks (18â¯weeks post-intervention), and compared between groups using repeated measures analysis. RESULTS: Outcome analysis included 112 participants (57 MBRP-A; 55 Control) who provided follow-up data. Participants were 41.0⯱â¯12.2â¯years old, 56.2% male, and 91% white. Prior to "quit date," they reported drinking on 59.4⯱â¯34.8% (averaging 6.1⯱â¯5.0 drinks/day) and heavy drinking (HD) on 50.4⯱â¯35.5% of days. Their drinking reduced after the "quit date" (before enrollment) to 0.4⯱â¯1.7% (HD: 0.1⯱â¯0.7%) of days. At 26â¯weeks, the MBRP-A and control groups reported any drinking on 11.5⯱â¯22.5% and 5.9⯱â¯11.6% of days and HD on 4.5⯱â¯9.3% and 3.2⯱â¯8.7% of days, respectively, without between-group differences (psâ¯≥â¯0.05) in drinking or related consequences during the follow-up period. Three MBRP-A participants reported "relapse," defined as three-consecutive HD days, during the study. Subgroup analysis indicated that greater adherence to session attendance and weekly home practice minutes were associated with improved outcomes. CONCLUSIONS: MBRP-A as an adjunct to usual-care did not show to improve outcomes in alcohol-dependent adults in early recovery compared to usual-care-alone; a return to drinking and relapse to HD were rare in both groups. However, greater adherence to MBRP-A intervention may improve long-term drinking-related outcomes.
Asunto(s)
Alcoholismo/terapia , Atención Plena , Negociación , Prevención Secundaria/métodos , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Atención Plena/métodos , Negociación/métodos , Resultado del TratamientoRESUMEN
OBJECTIVE: Opioid-treated chronic low back pain (CLBP) is debilitating, costly, and often refractory to existing treatments. This secondary analysis aims to pilot-test the hypothesis that mindfulness meditation (MM) can reduce economic burden related to opioid-treated CLBP. DESIGN: Twenty-six-week unblinded pilot randomized controlled trial, comparing MM, adjunctive to usual-care, to usual care alone. SETTING: Outpatient. PARTICIPANTS: Thirty-five adults with opioid-treated CLBP (≥30 morphine-equivalent mg/day) for 3 + months enrolled; none withdrew. INTERVENTION: Eight weekly therapist-led MM sessions and at-home practice. OUTCOME MEASURES: Costs related to self-reported healthcare utilization, medication use (direct costs), lost productivity (indirect costs), and total costs (direct + indirect costs) were calculated for 6-month pre-enrollment and postenrollment periods and compared within and between the groups. RESULTS: Participants (21 MM; 14 control) were 20 percent men, age 51.8 ± 9.7 years, with severe disability, opioid dose of 148.3 ± 129.2 morphine-equivalent mg/d, and individual annual income of $18,291 ± $19,345. At baseline, total costs were estimated at $15,497 ± 13,677 (direct: $10,635 ± 9,897; indirect: $4,862 ± 7,298) per participant. Although MM group participants, compared to controls, reduced their pain severity ratings and pain sensitivity to heat stimuli (p < 0.05), no statistically significant within-group changes or between-group differences in direct and indirect costs were noted. CONCLUSIONS: Adults with opioid-treated CLBP experience a high burden of disability despite the high costs of treatment. Although this pilot study did not show a statistically significant impact of MM on costs related to opioid-treated CLBP, MM can improve clinical outcomes and should be assessed in a larger trial with long-term follow-up.
Asunto(s)
Analgésicos Opioides/economía , Analgésicos Opioides/uso terapéutico , Dolor Crónico/economía , Dolor Crónico/terapia , Costos de los Medicamentos , Dolor de la Región Lumbar/economía , Dolor de la Región Lumbar/terapia , Meditación , Atención Plena/economía , Absentismo , Analgésicos Opioides/efectos adversos , Dolor Crónico/diagnóstico , Dolor Crónico/psicología , Análisis Costo-Beneficio , Evaluación de la Discapacidad , Eficiencia , Femenino , Humanos , Dolor de la Región Lumbar/diagnóstico , Dolor de la Región Lumbar/psicología , Masculino , Persona de Mediana Edad , Dimensión del Dolor , Proyectos Piloto , Ausencia por Enfermedad/economía , Factores de Tiempo , Resultado del Tratamiento , WisconsinRESUMEN
OBJECTIVES: To estimate the familiarity of black inner-city Chicagoans with pediatric folk beliefs identified by key informants. STUDY DESIGN: Five black staff members at an inner-city clinic identified 10 African American folk beliefs regarding pediatric care. A survey of 606 African American patients in Chicago assessed familiarity with these beliefs, and with medical recommendations regarding immunization and sleep position. RESULTS: The 2 medical recommendations were more familiar and more believed than any of the identified folk beliefs. The most widely known folk belief was that it is dangerous for a woman to go outdoors 4 to 6 weeks after she has a baby, which was familiar to 93% of respondents. The most believed cultural item was that it is bad to stand where an infant has to roll his eyes back to see you, which was familiar to 86% of respondents and thought true by 86% of those familiar with it. Respondents born in a southern state were significantly more likely to have heard of taping a coin over an umbilicus that sticks out (odds ratio [OR], 1.51; 95% confidence interval [Cl], 1.01-2.26; p = .045) and less likely to agree with infant back or side position for sleep (OR, 0.35; 95% CI, 0.14-0.85; p = .021). CONCLUSION: The widespread familiarity with specific folk beliefs in this population suggests that an understanding of these beliefs may be important for culturally competent providers of pediatric care in Chicago's inner city. Further research is needed to determine whether these findings are reproducible in other socioeconomic and geographic settings.
Asunto(s)
Negro o Afroamericano/psicología , Medicina Tradicional , Pediatría , Chicago , Características Culturales , Femenino , Humanos , MasculinoRESUMEN
UNLABELLED: The primary goal of this paper was to present a comprehensive picture of substance use disorders in a sample of patients receiving opioid therapy from their primary care physician. A second goal was to determine the relation of positive urine screens and aberrant drug behaviors to opioid use disorders. The study recruited 801 adults receiving daily opioid therapy from the primary care practices of 235 family physicians and internists in 6 health care systems in Wisconsin. The 6 most common pain diagnoses were degenerative arthritis, low back pain, migraine headaches, neuropathy, and fibromyalgia. The point prevalence of current (DSM-IV criteria in the past 30 days) substance abuse and/or dependence was 9.7% (n=78) and 3.8% (30) for an opioid use disorder. A logistic regression model found that current substance use disorders were associated with age between 18 and 30 (OR=6.17: 1.99 to 19.12), severity of lifetime psychiatric disorders (OR=6.17; 1.99 to 19.12), a positive toxicology test for cocaine (OR=5.92; 2.60 to 13.50) or marijuana (OR=3.52; 1.85 to 6.73), and 4 aberrant drug behaviors (OR=11.48; 6.13 to 21.48). The final model for opioid use disorders was limited to aberrant behaviors (OR=48.27; 13.63 to 171.04) as the other variables dropped out of the model. PERSPECTIVE: This study found that the frequency of opioid use disorders was 4 times higher in patients receiving opioid therapy compared with general population samples (3.8% vs 0.9%). The study also provides quantitative data linking aberrant drug behaviors to opioid use disorders.
Asunto(s)
Analgésicos Opioides/efectos adversos , Trastornos Relacionados con Opioides/epidemiología , Dolor Intratable/tratamiento farmacológico , Médicos de Familia/estadística & datos numéricos , Trastornos Relacionados con Sustancias/epidemiología , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Analgésicos Opioides/administración & dosificación , Causalidad , Enfermedad Crónica/terapia , Trastornos Relacionados con Cocaína/epidemiología , Comorbilidad , Esquema de Medicación , Humanos , Modelos Logísticos , Abuso de Marihuana/epidemiología , Tamizaje Masivo , Persona de Mediana Edad , Prevalencia , Factores de Riesgo , Urinálisis/estadística & datos numéricosRESUMEN
BACKGROUND: Complementary and alternative medicine (CAM) is an increasingly common therapy used to treat chronic pain syndromes. However; there is limited information on the utilization and efficacy of CAM therapy in primary care patients receiving long-term opioid therapy. METHOD: A survey of CAM therapy was conducted with a systematic sample of 908 primary care patients receiving opioids as a primary treatment method for chronic pain. Subjects completed a questionnaire designed to assess utilization, efficacy and costs of CAM therapies in this population. RESULTS: Patients were treated for a variety of pain problems including low back pain (38.4%), headaches (9.9%), and knee pain (6.5%); the average duration of pain was 16 years. The median morphine equivalent opioid dose was 41 mg/day, and the mean dose was 92 mg/day. Forty-four percent of the sample reported CAM therapy use in the past 12 months. Therapies utilized included massage therapy (27.3%, n = 248), chiropractic treatment (17.8%, n = 162), acupuncture (7.6%, n = 69), yoga (6.1%, n = 55), herbs and supplements (6.8%, n = 62), and prolotherapy (5.9%, n = 54). CAM utilization was significantly related to age female gender, pain severity income pain diagnosis of neck and upper back pain, and illicit drug use. Medical insurance covered chiropractic treatment (81.8%) and prolotherapy (87.7%), whereas patients primarily paid for other CAM therapies. Over half the sample reported that one or more of the CAM therapies were helpful. CONCLUSION: This study suggests CAM therapy is widely used by patients receiving opioids for chronic pain. Whether opioids can be reduced by introducing such therapies remains to be studied.