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1.
Allergol Immunopathol (Madr) ; 49(3): 173-184, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-33938204

RESUMEN

The post-viral acute cough is the most common symptom in childhood. Consequently, the use of cough relievers is frequent. Many products for treating cough contain natural components. An ancient tradition has always established herbal medicine and honey as effective and safe means to relieve cough. Nevertheless, very few studies adequately investigated the real effectiveness and safety of natural products in treating acute cough. There is some evidence, provided by pediatric randomized controlled trials, about honey, one multicomponent product (containing Plantagolanceolata, Grindelia robusta, Helichrysum italicum, and honey), and Pelargonium sidoides. Other group of substances, including glycerol and isolated natural compounds, can help manage cough but robust evidence still lacks in children. There is an urgent need to perform rigorous studies that confirm the natural products' efficacy and safety for relieving post-viral acute cough.Key points: Acute post-viral cough is prevalent in childhood and adolescence. There is a growing interest concerning the use of natural remedies for post-viral cough. Many herbal medicines could be used satisfactorily for this issue.


Asunto(s)
Antitusígenos/uso terapéutico , Apiterapia/métodos , Productos Biológicos/uso terapéutico , Tos/terapia , Preparaciones de Plantas/uso terapéutico , Enfermedad Aguda , Adolescente , Niño , Tos/tratamiento farmacológico , Tos/virología , Glicerol/uso terapéutico , Humanos , Extractos Vegetales/uso terapéutico , Aceites de Plantas/uso terapéutico , Saponinas/uso terapéutico
2.
Pediatr Allergy Immunol Pulmonol ; 33(1): 3-11, 2020 03.
Artículo en Inglés | MEDLINE | ID: mdl-33406022

RESUMEN

Upper respiratory tract infection (URTI)-associated acute cough is the most common symptom both in children and adults worldwide and causes economic and social problems with significant implications for the patient, the patient's family, and the health care system. New pathogenic mechanisms in acute cough, including the urge to cough (UTC) mechanisms, have been recently identified. The brainstem neural network, pharyngeal sensory innervation, airway mechanical stimulation, inflammatory mediators, and postnasal drip actively participate in the onset and maintenance of acute cough and the urge to cough phenomenon. However, there is still no effective pharmacological treatment capable of interfering with the pathophysiologic mechanisms involved in URTI-associated acute cough. Moreover, severe adverse events frequently occur in administering such cough medications, mainly in children. New evidence has been provided concerning polysaccharides, resins, and honey as potential cough relievers with high antitussive efficiency, effect on the UTC, and minimal side effects.


Asunto(s)
Antitusígenos/administración & dosificación , Apiterapia/métodos , Tos/tratamiento farmacológico , Infecciones del Sistema Respiratorio/tratamiento farmacológico , Enfermedad Aguda/terapia , Antitusígenos/economía , Tos/economía , Tos/inmunología , Costos de los Medicamentos , Miel , Humanos , Polisacáridos/administración & dosificación , Infecciones del Sistema Respiratorio/complicaciones , Infecciones del Sistema Respiratorio/economía , Infecciones del Sistema Respiratorio/inmunología
3.
Int J Dermatol ; 51(7): 790-5, 2012 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-22715822

RESUMEN

BACKGROUND: Skin diseases are very common in rural and urban areas of Ethiopia, and traditional preparations of plant origin might represent the only alternative to synthetic drugs. Improving knowledge of traditional medicines and assessing their safety and effectiveness is necessary. METHODS: We conducted a two-arm, randomized, double-blind, placebo-controlled trial assessing the efficacy of some cosmetic herbal preparations for common dermatologic problems: a 3% thyme essential oil antifungal cream and a 10% chamomile extract cream for eczema-like lesions. RESULTS: Ten subjects (66.5%) treated with the 3% thyme active cream were completely healed vs. four subjects (28.5%) from the placebo group (P=0.040). A large number of subjects treated with the chamomile cream were healed or improved, but no significant differences were found between active cream and placebo. A high rate of treatment acceptance was registered in both groups, no adverse effects were reported. CONCLUSIONS: A 3% thyme essential oil cream could represent a cheap and easily available opportunity to treat and heal mild to moderate cases of fungal infections; a common emollient cream could be a very effective intervention when treating mild to moderate cases of pityriasis alba and eczema-like lesions. Further research is needed.


Asunto(s)
Países en Desarrollo , Medicinas Tradicionales Africanas , Fitoterapia , Preparaciones de Plantas/uso terapéutico , Adolescente , Adulto , Anciano , Antifúngicos/uso terapéutico , Manzanilla , Niño , Preescolar , Fármacos Dermatológicos/uso terapéutico , Dermatomicosis/tratamiento farmacológico , Países en Desarrollo/economía , Eccema/tratamiento farmacológico , Etiopía , Femenino , Humanos , Lactante , Masculino , Medicinas Tradicionales Africanas/economía , Persona de Mediana Edad , Aceptación de la Atención de Salud , Fitoterapia/efectos adversos , Fitoterapia/economía , Pitiriasis/tratamiento farmacológico , Preparaciones de Plantas/efectos adversos , Thymus (Planta) , Adulto Joven
4.
Eur J Pediatr ; 162(12): 820-7, 2003 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-14513372

RESUMEN

UNLABELLED: For many families and their children, the use of complementary/alternative medicine (CAM) is an accepted adjunct or alternative to conventional therapy, even if data available in the literature regarding risks and adverse drug reactions (ADRs) pertaining to childhood populations are scarce. Moreover, despite widespread and increasing use of CAM, there are limited data on how paediatricians communicate with mothers and/or patients about CAM. Therefore, we report the studies available in the literature in the paediatric field and summarise what is known about ADRs and risks of CAM, taking into account in particular problems related to interactions between phytotherapy and conventional medicines and to counselling. CONCLUSION: from the analysis of the literature, some interesting aspects emerge: (1) the extent of CAM use in the paediatric field is increasingly sought by parents of children with chronic illnesses; (2) most parents who choose CAM medicine for their children believe that these therapies are "natural" and thus "safe" and (3) physicians often feel to know too little about CAM and wish to learn more for different reasons including "to dissuade whether the alternative method is unsafe and/or ineffective". Therefore, paediatricians should be prepared to discuss alternative therapies with parents, since talking about CAM may help to minimise the risks and to restrain parental misconceptions and doubts. Educational interventions for parents should also be performed to bring about a more aware use of traditional and alternative medicines.


Asunto(s)
Actitud Frente a la Salud , Terapias Complementarias , Madres , Pediatría , Relaciones Profesional-Familia , Australia , Niño , Enfermedad Crónica/tratamiento farmacológico , Comunicación , Terapias Complementarias/efectos adversos , Terapias Complementarias/estadística & datos numéricos , Interacciones Farmacológicas , Europa (Continente) , Femenino , Humanos , Madres/educación , América del Norte , Preparaciones de Plantas/efectos adversos , Preparaciones de Plantas/farmacología
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