RESUMEN
The hydroalcoholic extract of Maytenus krukovii bark was investigated for its in vitro mutageno-protective activities by means of the Ames Salmonella/microsome assay. The extract showed an inhibitory effect in both T98 and T100 strains against the mutagenic activity of promutagen 2-aminoanthracene but was not protective against directly acting mutagens sodium azide and 2-nitrofluorene. When tested as a radical scavenger and antioxidant it produced a dose-dependent inhibition. The extract did not show significant antibacterial properties, and was weakly active against dermatophyte and phytopathogenic fungi, but inhibited the growth of phytopathogen Pithyum ultimum.
Asunto(s)
Antifúngicos/farmacología , Antimutagênicos/farmacología , Maytenus , Fitoterapia , Extractos Vegetales/farmacología , Animales , Antibacterianos/administración & dosificación , Antibacterianos/farmacología , Antibacterianos/uso terapéutico , Antifúngicos/administración & dosificación , Antifúngicos/uso terapéutico , Antimutagênicos/administración & dosificación , Antimutagênicos/uso terapéutico , Antioxidantes/administración & dosificación , Antioxidantes/farmacología , Antioxidantes/uso terapéutico , Compuestos de Bifenilo , Relación Dosis-Respuesta a Droga , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Masculino , Pruebas de Sensibilidad Microbiana , Hongos Mitospóricos/efectos de los fármacos , Pruebas de Mutagenicidad , Picratos/química , Corteza de la Planta , Extractos Vegetales/administración & dosificación , Extractos Vegetales/uso terapéutico , Ratas , Ratas Sprague-Dawley , Salmonella/metabolismoRESUMEN
Nine samples of Glycyrrhiza glabra were collected in various sites of Calabria, Italy, with the aim to determine the variability in the confront of active constituents and in antibacterial and antifungal activities of the extracts. The samples showed remarkable differences in chemical composition and biological activity.
Asunto(s)
Antiinfecciosos/farmacología , Glycyrrhiza , Fitoterapia , Extractos Vegetales/farmacología , Antiinfecciosos/administración & dosificación , Antiinfecciosos/química , Antiinfecciosos/uso terapéutico , Bacterias Gramnegativas/efectos de los fármacos , Bacterias Grampositivas/efectos de los fármacos , Humanos , Italia , Pruebas de Sensibilidad Microbiana , Hongos Mitospóricos/efectos de los fármacos , Extractos Vegetales/administración & dosificación , Extractos Vegetales/química , Extractos Vegetales/uso terapéutico , Trichophyton/efectos de los fármacosRESUMEN
Oil of bergamot is receiving renewed popularity in aromatherapy. The biovariability of Citrus bergamia grown wild in Calabria (Italy) was investigated as far as chemical markers (linalool, linalyl acetate and bergapten) content and antioxidant and antifungal activities of the methanolic extracts. The average content in the markers presents slight variations with the altitude and more evident changes with the latitude of the areas of plant collection.