1.
Bioorg Med Chem Lett
; 14(5): 1235-7, 2004 Mar 08.
Artículo
en Inglés
| MEDLINE
| ID: mdl-14980672
RESUMEN
A series of benzo[g]quinoxaline-5,10-dione derivatives carrying a 7-dialkylaminomethyl substituent was synthesized and their in vitro cytotoxic activities were evaluated against four human cancer cell lines (HCT-15, SK-OV-3, MD-MB-468 and T-47D). The most active compound 9d showed cytotoxic activity comparable to that of doxorubicin against HCT-15 cancer cell line.